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White Sox vs. Twins Prediction and Odds - Apr 22, 2022

The Minnesota Twins square off with the Chicago White Sox in MLB action at Target Field on Friday, commencing at 8:10PM ET.
Bailey Ober (1-1, 3.27 ERA) will be on the bump for the Twins, while the White Sox are going with Michael Kopech (0-0, 1.00 ERA).
Dimers' best betting picks for White Sox vs. Twins, as well as game predictions and best odds, are detailed below.
Who will win White Sox vs. Twins?
Using high-tech computer power and data, Dimers.com has simulated Friday's White Sox-Twins MLB game 10,000 times.
Dimers' proven predictive analytics model, DimersBOT, gives the Twins a 53% chance of beating the White Sox.
More: Full Betting Analysis for White Sox vs. Twins
White Sox vs. Twins Odds
- Run Line: Twins -1.5 (+200), White Sox +1.5 (-208)
- Moneyline: Twins -102, White Sox -110
- Total: Over/Under 7.5 (+104/-115)
Run Line, Moneyline and Over/Under
The Twins are currently -1.5 favorites versus the White Sox, with +200 at BetMGM the best odds currently available.
For the underdog White Sox (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -208.
In a sign of how close this game is expected to be, both the Twins and White Sox are currently at minus-money betting odds on the moneyline.
FanDuel Sportsbook currently has the best moneyline odds for the Twins at -102, which means you can risk $102 to win $100, for a total payout of $202, if they get the W.
Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the White Sox at -110, where you can risk $110 to win $100, for a total payout of $210, if they come out on top.
The Over/Under is set at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at +104, while Caesars Sportsbook currently has the best odds for the Under at -115.
As always, check out all the online sportsbooks that are available in your state for the best MLB odds and lines.
According to DimersBOT, the White Sox (+1.5) are a 63% chance of covering the run line, while the Over/Under total of 7.5 runs is a 55% chance of going Over.
More: Live Win Probabilities for All Major Sports
Best Bets for White Sox vs. Twins
- Run Line: Twins -1.5 @ +200 via BetMGM (3.6% edge)
- Moneyline: Twins @ -102 via FanDuel Sportsbook (53% probability)
- Total: Over 7.5 @ +104 via FanDuel Sportsbook (55% probability) 🔥
If you see a 🔥, that means it's one of Dimers' best bets of the day across any sport.
Dimers' best bets are based on detailed simulations and betting intelligence to serve you the best possible plays every time.
Even though the White Sox are more likely to cover the run line, our best bet of Twins -1.5 is based on the chance of that happening, according to DimersBOT, and the best odds available.
White Sox vs. Twins Probabilities
Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Minnesota, and click or tap on See Matchup for more.
Dimers has full betting coverage of Friday's White Sox-Twins matchup, including pregame predictions, free picks, and live win probabilities.
Don't forget, DimersBOT updates frequently, so keep checking this page for any changes to our betting insights before White Sox vs. Twins on Friday April 22, 2022.
Best Betting Promo for White Sox vs. Twins
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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.
White Sox vs. Twins 2022 Game Info
When do the Twins play the White Sox?
- Date: Friday April 22, 2022
- Time: 8:10PM ET / 5:10PM PT
- Venue: Target Field
Ready to join an online sportsbook and start betting on MLB? Check out the best sports betting promos in your state.
What MLB games are on today?
The White Sox and Twins aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for each and every MLB game in our MLB Bet Hub section.
Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!
While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.
