White Sox vs. Royals Prediction and Odds - May 18, 2022

The Kansas City Royals take on the Chicago White Sox in MLB action at Kauffman Stadium on Wednesday, beginning at 8:10PM ET.

Zack Greinke (0-2, 3.52 ERA) will be on the bump for the Royals, up against Lucas Giolito (2-1, 2.70 ERA) for the White Sox.

Dimers' top betting picks for White Sox vs. Royals, plus game predictions and best odds, are detailed in this article.

Today's CHI White Sox vs. Kansas City betting preview is proudly sponsored by PointsBet, which has an outstanding 5x $100 Risk-Free Bets promo for new customers.

Who will win White Sox vs. Royals?

Using state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's White Sox-Royals MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the White Sox a 55% chance of getting the W against the Royals .

More: White Sox vs. Royals Simulated 10,000 Times

White Sox vs. Royals Game Odds

• Run Line: Royals +1.5 (-125), White Sox -1.5 (+115)
• Moneyline: Royals +135, White Sox -149
• Total: Over/Under 8 (-114/+100)

Run Line, Moneyline and Over/Under

The Royals are +1.5 underdogs against the White Sox, with -125 at PointsBet the best odds currently available.

For the favored White Sox (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +115.

DraftKings Sportsbook currently has the best moneyline odds for the Royals at +135, which means you can throw down $100 to profit $135, earning a total payout of $235, if they win.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the White Sox at -149, where you can risk $149 to win $100, for a total payout of $249, if they come out on top.

The Over/Under is set at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, while Caesars Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 8 runs is a 51% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for White Sox vs. Royals

• Run Line: White Sox -1.5 @ +115 via DraftKings Sportsbook
• Moneyline: Royals @ +135 via DraftKings Sportsbook (2.0% edge)
• Total: Under 8 @ +100 via Caesars Sportsbook

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every day of the year.

Even though the Royals are more likely to cover the run line, our best bet of White Sox -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

And while the White Sox are more likely to win the game, according to DimersBOT, taking the Royals moneyline is the best option because of the 2.0% edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges seen on Dimers.com is crucial to being profitable in the long run.

Furthermore, despite the Over being more likely to hit on this occasion, Under 8 is our best bet owing to the better odds (+100) that are available from Caesars Sportsbook.

White Sox vs. Royals Betting Guide

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Kansas City, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's White Sox-Royals matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so check this page for any changes to our betting insights ahead of White Sox vs. Royals on Wednesday May 18, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

White Sox vs. Royals 2022 Game Info

Wednesday's action between the Royals and White Sox at Kauffman Stadium is scheduled to begin at 8:10PM ET.

• Date: Wednesday May 18, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Kauffman Stadium

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What MLB games are on today?

The White Sox and Royals aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for each and every MLB game in our MLB Bet Hub page.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.