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Western Michigan vs. SIUE prediction: SIU-Edwardsville favored to win men's college basketball matchup [12/6/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Western Michigan vs SIUE predictions for college basketball Saturday.
SIUE and Western Michigan will lock horns in men's college basketball action at Sam M. Vadalabene Center on Saturday, starting at 2:00PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts SIU-Edwardsville as the most likely winner of the Western Michigan vs. SIUE game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Western Michigan vs. SIUE prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball matchup between Western Michigan and SIUE 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model currently gives SIU-Edwardsville a 72% chance of defeating Western Michigan. Our predicted final score has SIU-Edwardsville winning 77-71.
According to our model, Western Michigan (+6.5) has a 51% chance of covering the spread, while the 143.5-point over/under has a 56% chance of going over.
Western Michigan vs. SIUE odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Western Michigan | SIUE |
|---|---|---|
| Spread | +6.5 (-105) | -6.5 (-112) |
| Moneyline | +245 | -290 |
| Total | o143.5 (-112) | u143.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Western Michigan vs. SIUE picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Western Michigan +6.5 | -105 |
| Moneyline | Western Michigan | +245 |
| Total | Over 143.5 | -112 |
According to our men's college basketball best bets, the top play to make on this game is Over 143.5 total points.
Western Michigan vs. SIUE game-day updates and essential details
Saturday's men's college basketball game between SIUE and Western Michigan at Sam M. Vadalabene Center is scheduled to start at 2:00PM ET.
- Who: Western Michigan vs. SIU-Edwardsville
- Date: Saturday, December 6, 2025
- Time: 2:00PM ET/11:00AM PT
- Venue: Sam M. Vadalabene Center
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Conclusion
We predict SIU-Edwardsville, with a 72% win probability, will likely beat Western Michigan on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Western Michigan vs. SIU-Edwardsville insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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