Western Carolina vs. USC Upstate prediction: Western Carolina favored to win men's college basketball matchup [12/6/2025]

USC Upstate will square off with Western Carolina, in what is expected to be a close Men's College Basketball game, at G.B. Hodge Center on Saturday, commencing at 2:00PM ET.

Based on updated simulations, Dimers' advanced college basketball model gives Western Carolina a slight edge with a 54% win probability over USC Upstate.

This article offers a closer look at Saturday's Western Carolina vs. USC Upstate matchup, including an expanded look at the predicted score, best bets and picks.

Western Carolina vs. USC Upstate prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Western Carolina and USC Upstate 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Western Carolina a 54% chance of beating USC Upstate. Our predicted final score has Western Carolina winning 77-76.

According to our model, USC Upstate (+1.5) has a 51% chance of covering the spread, while the 151.5-point over/under has a 53% chance of going over.

Western Carolina vs. USC Upstate odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Western Carolina vs. USC Upstate picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: