West Virginia vs. Iowa State prediction: Why Iowa State is favored to win men's college basketball matchup [1/2/2026]

Iowa State and West Virginia are scheduled to meet in men's college basketball action at James H. Hilton Coliseum on Friday, with tipoff at 9:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Iowa State as the most likely winner of the West Virginia vs. Iowa State game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

West Virginia vs. Iowa State prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Friday's NCAA basketball game between West Virginia and Iowa State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iowa State a 96% chance of beating West Virginia. Our predicted final score has Iowa State winning 81-61.

According to our model, Iowa State (-18.5) has a 54% chance of covering the spread, while the 140.5-point over/under has a 53% chance of going over.

West Virginia vs. Iowa State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

West Virginia vs. Iowa State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: