Villanova vs. Wisconsin prediction: Why Wisconsin is favored to win men's college basketball matchup [12/19/2025]

Wisconsin will face Villanova in men's college basketball action at Fiserv Forum on Friday, commencing at 8:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Wisconsin as the most likely winner of the Villanova vs. Wisconsin game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Villanova vs. Wisconsin prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Friday's NCAA basketball game between Villanova and Wisconsin 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Wisconsin a 60% chance of beating Villanova. Our predicted final score has Wisconsin winning 78-75.

According to our model, Villanova (+4.5) has a 55% chance of covering the spread, while the over/under total of 152.5 points has a 53% chance of going over.

Villanova vs. Wisconsin odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Villanova vs. Wisconsin picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: