Villanova vs. DePaul CBB Predictions and Odds - Jan 8, 2022

DePaul takes on the favored Villanova in College Basketball action at Wintrust Arena on Saturday, starting at 2:00PM EST.

Dimers' top betting picks for Villanova vs. DePaul, plus game predictions and best odds, are featured below.

Who will win Villanova vs. DePaul?

Based on high-tech machine learning and data, Dimers.com has simulated Saturday's Villanova-DePaul NCAA Basketball matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives Villanova a 76% chance of winning against DePaul.

MORE: Free Betting Guide for Villanova vs. DePaul

Point Spread, Moneyline and Over/Under

DePaul is listed as the +9.5 underdog versus Villanova, with -110 at BetMGM the best odds available.

For the favored Villanova (-9.5) to cover the spread, BetMGM also has the best odds on offer at -110.

BetMGM has the best moneyline odds for DePaul at +340. That means you can throw down $100 to profit $340, earning a total payout of $440, if it wins.

Meanwhile, DraftKings Sportsbook has the best moneyline odds for Villanova at -400, where you can risk $400 to win $100, for a total payout of $500, if it comes out on top.

The Over/Under is set at 137.5 with BetMGM, which has the best odds for the Over at -110, as well as the best odds for the Under at -110.

As always, make sure you check the sportsbooks you have access to in your state for the best College Basketball odds and lines.

According to DimersBOT, DePaul (+9.5) is a 63% chance of covering the spread, while the Over/Under total of 137.5 points is a 53% chance of going Over.

MORE: Predictions for Every CBB Matchup

Best Bets for Villanova vs. DePaul

• Spread: DePaul +9.5 at -110 with BetMGM (63% probability) 🔥
• Moneyline: DePaul Win at +340 with BetMGM (1.9% edge)
• Over/Under: Over 137.5 at -110 with BetMGM (53% probability)

Every time you see a 🔥, you know it's one of Dimers' best bets today across all sports.

While Villanova is more likely to win the game, according to DimersBOT, betting on DePaul moneyline is the best option due to the 1.9% edge found when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges seen here at Dimers is pivotal to being a profitable sports bettor in the long run.

Villanova vs. DePaul Score Prediction

Dimers.com's predicted final score for Villanova vs. DePaul at Wintrust Arena this Saturday has Villanova winning 72-65.

Use our interactive widget below to see the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full betting coverage of Saturday's Villanova-DePaul matchup, including pre-game predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting insights before Villanova vs. DePaul on Saturday January 8, 2022.

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Villanova vs. DePaul 2022 CBB Game Info

When does DePaul play Villanova in College Basketball?

• Date: Saturday January 8, 2022
• Time: 2:00PM EST / 11:00AM PST
• Venue: Wintrust Arena

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Want more CBB predictions like this?

To get more NCAA Basketball betting previews like you've just read for Villanova vs. DePaul, all you've gotta do is visit Dimers' College Basketball Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the most comprehensive CBB betting previews out there. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.