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UTSA vs. USC prediction: USC favored to win men's college basketball matchup [12/17/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get UTSA vs USC predictions for college basketball Wednesday.
Men's college basketball action continues on Wednesday at 9:00 PM ET as UTSA looks to defy the odds against USC in men's college basketball action at Galen Center.
Based on updated simulation results, Dimers' advanced college basketball model predicts USC as the most likely winner of the UTSA vs. USC game.
This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
UTSA vs. USC prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball game between UTSA and USC 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives USC a 98% chance of beating UTSA. Our predicted final score has USC winning 91-66.
According to our model, USC (-24.5) has a 52% chance of covering the spread, while the over/under total of 158.5 points has a 52% chance of going over.
UTSA vs. USC odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | UTSA | USC |
|---|---|---|
| Spread | +24.5 (-110) | -24.5 (-110) |
| Moneyline | +2500 | -5000 |
| Total | o158.5 (-105) | u158.5 (-115) |
All odds are correct at the time of publication and are subject to change.
UTSA vs. USC picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | USC -24.5 | -110 |
| Moneyline | USC | -5000 |
| Total | Over 158.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 158.5 total points.
UTSA vs. USC game-day updates and essential details
Wednesday's men's college basketball action between USC and UTSA at Galen Center is scheduled to begin at 9:00 PM ET.
- Who: UTSA vs. USC
- Date: Wednesday, December 17, 2025
- Time: 9:00 PM ET/6:00PM PT
- Venue: Galen Center
Conclusion
We predict USC, with a 98% win probability, will likely beat UTSA on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate UTSA vs. USC insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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