USC vs. Michigan prediction: Why Michigan is favored to win men's college basketball matchup [1/2/2026]

Men's college basketball action continues on Friday at 7:00 PM ET as USC looks to defy the odds against Michigan in men's college basketball action at Crisler Center.

Based on updated simulation results, Dimers' advanced college basketball model projects Michigan as the most likely winner of the USC vs. Michigan game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

USC vs. Michigan prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Friday's NCAA basketball matchup between USC and Michigan 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Michigan a 96% chance of defeating USC. Our predicted final score has Michigan winning 92-69.

According to our model, Michigan (-21.5) has a 53% chance of covering the spread, while the 169.5-point over/under has a 55% chance of staying under.

USC vs. Michigan odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

USC vs. Michigan picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: