USC Upstate vs. Youngstown State prediction: Youngstown State favored to win men's college basketball matchup [12/20/2025]

Youngstown State will take on USC Upstate in men's college basketball action at Beeghly Center on Saturday, beginning at 1:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Youngstown State as the most likely winner of the USC Upstate vs. Youngstown State game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

USC Upstate vs. Youngstown State prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between USC Upstate and Youngstown State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Youngstown State a 77% chance of defeating USC Upstate. Our predicted final score has Youngstown State winning 75-67.

According to our model, the bookmakers have got it right, and USC Upstate and Youngstown State each have a 50% chance of covering the spread, while the over/under total of 141.5 points has a 53% chance of going over.

USC Upstate vs. Youngstown State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

USC Upstate vs. Youngstown State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: