Twins vs. Orioles Prediction and Odds - May 5, 2022

The Baltimore Orioles and Minnesota Twins are scheduled to meet in MLB at Oriole Park at Camden Yards on Thursday, starting at 7:05PM ET.

Spenser Watkins (0-0, 2.55 ERA) will get the ball for the Orioles, pitting him against Chris Archer (0-0, 2.94 ERA) for the Twins.

Dimers' top betting picks for Twins vs. Orioles, as well as game predictions and best odds, are featured in this article.

Today's Minnesota vs. Baltimore betting analysis is sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new users.

Who will win Twins vs. Orioles?

Using advanced computer power and data, Dimers.com has simulated Thursday's Twins-Orioles MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, currently gives the Twins a 57% chance of beating the Orioles.

More: Twins vs. Orioles Simulated 10K Times

Twins vs. Orioles Odds

• Run Line: Orioles +1.5 (-120), Twins -1.5 (+105)
• Moneyline: Orioles +140, Twins -150
• Total: Over/Under 8.5 (-110/-104)

Run Line, Moneyline and Over/Under

The Orioles are +1.5 underdogs against the Twins, with -120 at BetMGM the best odds currently available.

For the favored Twins (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +105.

Caesars Sportsbook currently has the best moneyline odds for the Orioles at +140. That means you can bet $100 to profit $140, earning a total payout of $240, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Twins at -150, where you can risk $150 to win $100, for a total payout of $250, if they come out on top.

The Over/Under for total runs scored is set at 8.5 with BetMGM, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Orioles (+1.5) are a 55% chance of covering the run line, while the 8.5-run Over/Under is a 52% chance of going Over.

More: Predictions for Every MLB Game

Best Bets for Twins vs. Orioles

• Run Line: Orioles +1.5 @ -120 via BetMGM (55% probability)
• Moneyline: Orioles @ +140 via Caesars Sportsbook (0.9% edge)
• Total: Over 8.5 @ -110 via BetMGM (52% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to serve you the best possible plays every time.

While the Twins are more likely to win the game, according to DimersBOT, taking the Orioles moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being profitable in the long run.

Twins vs. Orioles Probabilities

Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Minnesota vs. Baltimore, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's Twins-Orioles matchup, including pregame predictions, best betting picks, and live scores.

Don't forget, DimersBOT updates frequently, so check this article for the latest betting analysis ahead of Twins vs. Orioles on Thursday May 5, 2022.

Risk-Free Bet for Twins vs. Orioles

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Twins vs. Orioles 2022 Game Info

When do the Orioles play the Twins?

• Date: Thursday May 5, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Oriole Park at Camden Yards

Looking to join an online sportsbook and start betting on MLB? We've reviewed the best available sign-up offers in every legal betting state.

What MLB games are on today?

The Twins and Orioles aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for each and every MLB matchup via our MLB Predictions section.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.