Twins vs. Guardians Prediction and Odds - Jun 29, 2022

The Cleveland Guardians and Minnesota Twins are scheduled to meet in MLB at Progressive Field on Wednesday, starting at 7:10PM ET.

The Guardians will send Cal Quantrill (4-4, 3.76 ERA) to the mound, up against Dylan Bundy (4-4, 4.80 ERA) for the Twins.

Dimers' free betting picks for Twins vs. Guardians, as well as game predictions and betting odds, are featured in this article.

Who will win Twins vs. Guardians?

Using trusted computer power and data, Dimers.com has simulated Wednesday's Twins-Guardians MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Guardians a 51% chance of getting the W against the Twins.

More: Twins vs. Guardians Simulated 10K Times

Twins vs. Guardians Game Odds

• Run Line: Guardians +1.5 (-200), Twins -1.5 (+165)
• Moneyline: Guardians -125, Twins +110
• Total: Over/Under 9 (+100/-120)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs against the Twins, with -200 at BetMGM the best odds currently available.

For the favored Twins (-1.5) to cover the run line, BetMGM also has the best odds currently on offer at +165.

BetMGM currently has the best moneyline odds for the Guardians at -125. That means you can risk $125 to win $100, for a total payout of $225, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Twins at +110, where you can bet $100 to profit $110, earning a total payout of $210, if they win.

The Over/Under is set at 9 with BetMGM, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all of the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 63% chance of covering the run line, while the 9-run Over/Under is a 51% chance of going Under.

More: Track Your Bets via Bet Center

Best Bets for Twins vs. Guardians

• Run Line: Twins -1.5 @ +165 via BetMGM
• Moneyline: Twins @ +110 via DraftKings Sportsbook (0.9% edge)
• Total: Over 9 @ +100 via BetMGM

Dimers' best bets are based on detailed simulations and gambling expertise to bring you the best possible plays 24/7/365.

Even though the Guardians are more likely to cover the run line, our best bet of Twins -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

And while the Guardians are more likely to win the game, according to DimersBOT, betting on the Twins moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is pivotal to being profitable in the long run.

Furthermore, despite the Under being more likely to hit on this occasion, Over 9 is our best bet on account of the better odds (+100) that are available from BetMGM.

Twins vs. Guardians Probabilities

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Minnesota vs. Cleveland, and click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Twins-Guardians matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep checking this page for any changes to our betting insights ahead of Twins vs. Guardians on Wednesday June 29, 2022.

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Twins vs. Guardians 2022 Game Info

Wednesday's matchup between the Guardians and Twins at Progressive Field is scheduled to begin at 7:10PM ET.

• Who: Cleveland Guardians vs. Minnesota Twins
• Date: Wednesday June 29, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Progressive Field

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What other MLB games are on today?

The Twins and Guardians aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for every single MLB matchup in our MLB Bet Hub section.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.