Tigers vs. Guardians Prediction and Odds - May 20, 2022

MLB action continues on Friday at 7:10PM ET as the Detroit Tigers take on the Cleveland Guardians at Progressive Field.

The Guardians will have Aaron Civale (1-3, 9.85 ERA) start, while the Tigers will counter with Tarik Skubal (3-2, 2.50 ERA).

Dimers' free betting picks for Tigers vs. Guardians, as well as game predictions and best odds, are featured in this article.

This Detroit vs. Cleveland betting analysis is proudly sponsored by PointsBet, which has a great 5x $100 Risk-Free Bets offer for new customers.

Who will win Tigers vs. Guardians?

Based on advanced machine learning and data, Dimers.com has simulated Friday's Tigers-Guardians MLB matchup 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Guardians a 54% chance of beating the Tigers .

More: Tigers vs. Guardians Simulated 10,000 Times

Tigers vs. Guardians Current Odds

• Run Line: Guardians +1.5 (-179), Tigers -1.5 (+165)
• Moneyline: Guardians -115, Tigers +102
• Total: Over/Under 8.5 (-118/-104)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs against the Tigers, with -179 at Caesars Sportsbook the best odds currently available.

For the favored Tigers (-1.5) to cover the run line, PointsBet has the best odds currently on offer at +165.

Caesars Sportsbook currently has the best moneyline odds for the Guardians at -115, which means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Tigers at +102, where you can put down $100 to profit $102, earning a total payout of $202, if they win.

The Over/Under sits at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, as well as the best odds for the Under at -104.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 66% chance of covering the run line, while the Over/Under total of 8.5 runs is a 53% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Tigers vs. Guardians

• Run Line: Guardians +1.5 @ -179 via Caesars Sportsbook (66% probability)
• Moneyline: Guardians @ -115 via Caesars Sportsbook (54% probability)
• Total: Over 8.5 @ -118 via FanDuel Sportsbook (53% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in America.

Tigers vs. Guardians Probabilities

Use our widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Detroit vs. Cleveland, and click or tap on See Matchup for more.

Dimers has full betting coverage of Friday's Tigers-Guardians matchup, including pregame predictions, best betting picks, and live scores.

Don't forget, DimersBOT updates regularly, so keep an eye on this page for the latest betting insights ahead of Tigers vs. Guardians on Friday May 20, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Tigers vs. Guardians 2022 Game Info

Friday's game between the Guardians and Tigers at Progressive Field is scheduled to commence at 7:10PM ET.

• Date: Friday May 20, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Progressive Field

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Want more MLB predictions like this?

So, you liked our Tigers vs. Guardians betting analysis? Awesome. Did you know our MLB Betting News page has a detailed betting preview for every MLB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find value in the markets, which allows us to produce the most reliable MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not take a look around?

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.