Tigers vs. Astros Prediction and Odds - May 6, 2022

The Houston Astros square off with the Detroit Tigers in MLB action at Minute Maid Park on Friday, commencing at 8:10PM ET.

Luis Garcia (1-1, 4.15 ERA) will get the ball for the Astros, while the Tigers will counter with Beau Brieske (0-1, 3.60 ERA).

Dimers' best betting picks for Tigers vs. Astros, as well as game predictions and best odds, are detailed in this article.

Today's Detroit vs. Houston betting preview is brought to you by PointsBet, which has an awesome 5x $100 Risk-Free Bets offer for new users.

Who will win Tigers vs. Astros?

Based on high-tech machine learning and data, Dimers.com has simulated Friday's Tigers-Astros MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Astros a 64% chance of winning against the Tigers.

More: Tigers vs. Astros Simulated 10K Times

Tigers vs. Astros Odds

• Run Line: Astros -1.5 (-110), Tigers +1.5 (+105)
• Moneyline: Astros -225, Tigers +200
• Total: Over/Under 8 (-115/+100)

Run Line, Moneyline and Over/Under

The Astros are listed as -1.5 favorites versus the Tigers, with -110 at BetMGM the best odds currently available.

For the underdog Tigers (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +105.

BetMGM currently has the best moneyline odds for the Astros at -225. That means you can risk $225 to win $100, for a total payout of $325, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Tigers at +200, where you can bet $100 to profit $200, earning a total payout of $300, if they win.

The Over/Under for total runs scored sits at 8 with BetMGM, which currently has the best odds for the Over at -115, while PointsBet currently has the best odds for the Under at +100.

As always, make sure you check all the online sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Tigers (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 8 runs is a 54% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Tigers vs. Astros

• Run Line: Tigers +1.5 @ +105 via DraftKings Sportsbook (54% probability) 🔥
• Moneyline: Tigers @ +200 via DraftKings Sportsbook (2.5% edge)
• Total: Over 8 @ -115 via BetMGM (54% probability)

Every time you see a 🔥, you know you've found one of our best bets today across any sport.

Dimers' best bets are based on world-class simulations and wagering intelligence to serve you the best possible plays 24/7/365.

While the Astros are more likely to win the game, according to DimersBOT, betting on the Tigers moneyline is the best option because of the 2.5% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is one of the keys to being a profitable sports bettor in the long run.

Tigers vs. Astros Betting Guide

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Detroit vs. Houston, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Tigers-Astros matchup, including pregame predictions, top betting picks, and live scores.

Remember, DimersBOT updates often, so check this page for any changes to our betting insights before Tigers vs. Astros on Friday May 6, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Tigers vs. Astros 2022 Game Info

When do the Astros play the Tigers?

• Date: Friday May 6, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Minute Maid Park

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Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Tigers vs. Astros, all you've gotta do is visit Dimers' MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can write the best MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.