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Stetson vs. South Carolina prediction: South Carolina favored to win men's college basketball matchup [12/6/2025]

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Written by Dave Garofolo

Get Stetson vs South Carolina predictions for college basketball Saturday.

Stetson-South Carolina Predictions and Game Preview.
Stetson vs. South Carolina men's college basketball prediction for Saturday, December 6, 2025.

South Carolina and Stetson are scheduled to meet in men's college basketball action at Colonial Life Arena on Saturday, starting at 2:00PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects South Carolina as the most likely winner of the Stetson vs. South Carolina game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Stetson vs. South Carolina prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between Stetson and South Carolina 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives South Carolina a 97% chance of beating Stetson. Our predicted final score has South Carolina winning 82-61.

According to our model, Stetson (+22.5) has a 52% chance of covering the spread, while the over/under total of 142.5 points has a 53% chance of going over.

 

Stetson vs. South Carolina odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Stetson South Carolina
Spread +22.5 (-110) -22.5 (-105)
Moneyline +2000 -6998
Total o142.5 (-105) u142.5 (-104)

All odds are correct at the time of publication and are subject to change.

Stetson vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Stetson +22.5 -110
Moneyline South Carolina -6998
Total Over 142.5 -105

According to our best men's college basketball bets, the top play to make on this game is Over 142.5 total points.

 

Stetson vs. South Carolina game-day updates and essential details

Saturday's men's college basketball action between South Carolina and Stetson at Colonial Life Arena is scheduled to commence at 2:00PM ET.

  • Who: Stetson vs. South Carolina
  • Date: Saturday, December 6, 2025
  • Time: 2:00PM ET/11:00AM PT
  • Venue: Colonial Life Arena

 

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Conclusion

We predict South Carolina, with a 97% win probability, will likely beat Stetson on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Stetson vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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