Stetson vs. South Carolina prediction: South Carolina favored to win men's college basketball matchup [12/6/2025]

South Carolina and Stetson are scheduled to meet in men's college basketball action at Colonial Life Arena on Saturday, starting at 2:00PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts South Carolina as the most likely winner of the Stetson vs. South Carolina game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Stetson vs. South Carolina prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball game between Stetson and South Carolina 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives South Carolina a 97% chance of defeating Stetson. Our predicted final score has South Carolina winning 82-61.

According to our model, Stetson (+21.5) has a 52% chance of covering the spread, while the 141.5-point over/under has a 53% chance of going over.

Stetson vs. South Carolina odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Stetson vs. South Carolina picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: