Stetson vs. Oklahoma prediction: Oklahoma favored to win men's college basketball matchup [12/22/2025]

Men's college basketball action continues on Monday at 9:00 PM ET as Stetson takes on the favored Oklahoma in men's college basketball action at Lloyd Noble Center.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Oklahoma as the most likely winner of the Stetson vs. Oklahoma game.

This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Stetson vs. Oklahoma prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Monday's NCAA basketball matchup between Stetson and Oklahoma 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Oklahoma a 99% chance of beating Stetson. Our predicted final score has Oklahoma winning 88-59.

According to our model, Stetson (+31.5) has a 53% chance of covering the spread, while the over/under total of 146.5 points has a 52% chance of going over.

Stetson vs. Oklahoma odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Stetson vs. Oklahoma picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: