St. Bonaventure vs. Buffalo prediction: St. Bonaventure favored to win men's college basketball matchup [12/6/2025]

Buffalo will take on the favored St. Bonaventure in men's college basketball action at Alumni Arena on Saturday, commencing at 2:00PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts St. Bonaventure as the most likely winner of the St. Bonaventure vs. Buffalo game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

St. Bonaventure vs. Buffalo prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball game between St. Bonaventure and Buffalo 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives St. Bonaventure a 66% chance of defeating Buffalo. Our predicted final score has St. Bonaventure winning 73-69.

According to our model, Buffalo (+5.5) has a 58% chance of covering the spread, while the 141.5-point over/under has a 53% chance of going over.

St. Bonaventure vs. Buffalo odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

St. Bonaventure vs. Buffalo picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: