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Southern Miss vs. Ole Miss prediction: Ole Miss favored to win men's college basketball matchup [12/13/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Southern Miss vs Ole Miss predictions for college basketball Saturday.
Ole Miss will take on Southern Miss in men's college basketball action at Mississippi Coast Coliseum on Saturday, starting at 3:00PM ET.
Based on the latest simulations, Dimers' proven college basketball model predicts Ole Miss as the most likely winner of the Southern Miss vs. Ole Miss game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Southern Miss vs. Ole Miss prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Southern Miss and Ole Miss 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Ole Miss a 91% chance of beating Southern Miss. Our predicted final score has Ole Miss winning 77-63.
According to our model, Ole Miss (-12.5) has a 55% chance of covering the spread, while the over/under total of 138.5 points has a 53% chance of going over.
Southern Miss vs. Ole Miss odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Southern Miss | Ole Miss |
|---|---|---|
| Spread | +12.5 (-105) | -12.5 (-115) |
| Moneyline | +720 | -1000 |
| Total | o138.5 (-110) | u138.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Southern Miss vs. Ole Miss picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Ole Miss -12.5 | -115 |
| Moneyline | Ole Miss | -1000 |
| Total | Over 138.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Ole Miss -12.5 at the spread.
Southern Miss vs. Ole Miss game-day updates and essential details
Saturday's men's college basketball action between Ole Miss and Southern Miss at Mississippi Coast Coliseum is scheduled to begin at 3:00PM ET.
- Who: Southern Miss vs. Ole Miss
- Date: Saturday, December 13, 2025
- Time: 3:00PM ET/12:00PM PT
- Venue: Mississippi Coast Coliseum
Conclusion
We predict Ole Miss, with a 91% win probability, will likely beat Southern Miss on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Southern Miss vs. Ole Miss insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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