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Southern Indiana vs. SIUE prediction: SIU-Edwardsville favored to win men's college basketball matchup [1/1/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Southern Indiana vs SIUE predictions for college basketball Thursday.
SIUE and Southern Indiana will meet in men's college basketball action at Sam M. Vadalabene Center on New Year's Day, starting at 4:30 PM ET.
Based on the latest simulations, Dimers' advanced college basketball model projects SIU-Edwardsville as the most likely winner of the Southern Indiana vs. SIUE game.
This article offers an expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks.
Southern Indiana vs. SIUE prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the result of Thursday's NCAA basketball matchup between Southern Indiana and SIUE 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives SIU-Edwardsville an 87% chance of defeating Southern Indiana. Our predicted final score has SIU-Edwardsville winning 75-63.
According to our model, SIU-Edwardsville (-10.5) has a 54% chance of covering the spread, while the over/under total of 137.5 points has a 54% chance of going over.
Southern Indiana vs. SIUE odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Southern Indiana | SIUE |
|---|---|---|
| Spread | +10.5 (-118) | -10.5 (+100) |
| Moneyline | +430 | -550 |
| Total | o137.5 (-105) | u137.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Southern Indiana vs. SIUE picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | SIU-Edwardsville -10.5 | +100 |
| Moneyline | SIU-Edwardsville | -550 |
| Total | Over 137.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is SIU-Edwardsville -10.5 at the spread.
Southern Indiana vs. SIUE game-day updates and essential details
Thursday's men's college basketball action between SIUE and Southern Indiana at Sam M. Vadalabene Center is scheduled to begin at 4:30 PM ET.
- Who: Southern Indiana vs. SIU-Edwardsville
- Date: Thursday, January 1, 2026
- Time: 4:30 PM ET/1:30PM PT
- Venue: Sam M. Vadalabene Center
Conclusion
We predict SIU-Edwardsville, with an 87% win probability, will likely beat Southern Indiana on New Year's Day.
AI and automation have enhanced this article to quickly deliver accurate Southern Indiana vs. SIU-Edwardsville insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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