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USF vs. Alabama prediction: Why Alabama is favored to win men's college basketball matchup [12/17/2025]

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Written by Mac Douglass

Get USF vs Alabama predictions for college basketball Wednesday.

USF-Alabama Predictions and Game Preview.
USF vs. Alabama men's college basketball prediction for Wednesday, December 17, 2025.

Alabama will face USF in men's college basketball action at Coleman Coliseum on Wednesday, commencing at 8:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Alabama as the most likely winner of the USF vs. Alabama game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

USF vs. Alabama prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between USF and Alabama 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Alabama an 89% chance of beating South Florida. Our predicted final score has Alabama winning 92-76.

According to our model, Alabama (-14.5) has a 53% chance of covering the spread, while the over/under total of 178.5 points has a 53% chance of staying under.

 

USF vs. Alabama odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type USF Alabama
Spread +14.5 (-105) -14.5 (-108)
Moneyline +890 -1100
Total o178.5 (-105) u178.5 (-110)

All odds are correct at the time of publication and are subject to change.

USF vs. Alabama picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Alabama -14.5 -108
Moneyline South Florida +890
Total Under 178.5 -110

According to our men's college basketball best bets, the top play to make on this game is Alabama -14.5 at the spread.

 

USF vs. Alabama game-day updates and essential details

Wednesday's men's college basketball matchup between Alabama and USF at Coleman Coliseum is scheduled to begin at 8:00 PM ET.

  • Who: South Florida vs. Alabama
  • Date: Wednesday, December 17, 2025
  • Time: 8:00 PM ET/5:00PM PT
  • Venue: Coleman Coliseum

Conclusion

We predict Alabama, with an 89% win probability, will likely beat South Florida on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate South Florida vs. Alabama insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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