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USF vs. Alabama prediction: Why Alabama is favored to win men's college basketball matchup [12/17/2025]
Get USF vs Alabama predictions for college basketball Wednesday.

Alabama will face USF in men's college basketball action at Coleman Coliseum on Wednesday, commencing at 8:00 PM ET.
Based on updated simulations, Dimers' advanced college basketball model predicts Alabama as the most likely winner of the USF vs. Alabama game.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
USF vs. Alabama prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between USF and Alabama 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Alabama an 89% chance of beating South Florida. Our predicted final score has Alabama winning 92-76.
According to our model, Alabama (-14.5) has a 53% chance of covering the spread, while the over/under total of 178.5 points has a 53% chance of staying under.
USF vs. Alabama odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | USF | Alabama |
|---|---|---|
| Spread | +14.5 (-105) | -14.5 (-108) |
| Moneyline | +890 | -1100 |
| Total | o178.5 (-105) | u178.5 (-110) |
All odds are correct at the time of publication and are subject to change.
USF vs. Alabama picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Alabama -14.5 | -108 |
| Moneyline | South Florida | +890 |
| Total | Under 178.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Alabama -14.5 at the spread.
USF vs. Alabama game-day updates and essential details
Wednesday's men's college basketball matchup between Alabama and USF at Coleman Coliseum is scheduled to begin at 8:00 PM ET.
- Who: South Florida vs. Alabama
- Date: Wednesday, December 17, 2025
- Time: 8:00 PM ET/5:00PM PT
- Venue: Coleman Coliseum
Conclusion
We predict Alabama, with an 89% win probability, will likely beat South Florida on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate South Florida vs. Alabama insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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