South Carolina State vs. Tennessee prediction: Why Tennessee is favored to win men's college basketball matchup [12/30/2025]

Tennessee will square off with South Carolina State in men's college basketball action at Thompson-Boling Arena on Tuesday, starting at 8:00 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Tennessee as the most likely winner of the South Carolina State vs. Tennessee game.

This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.

South Carolina State vs. Tennessee prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between South Carolina State and Tennessee 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Tennessee a 100% chance of defeating South Carolina State. Our predicted final score has Tennessee winning 90-57.

According to our model, South Carolina State (+44.5) has a 62% chance of covering the spread, while the over/under total of 148.5 points has an equal 50-50 chance of hitting.

South Carolina State vs. Tennessee odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Carolina State vs. Tennessee picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: