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South Carolina State vs. South Carolina prediction: South Carolina favored to win men's college basketball matchup [12/22/2025]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get South Carolina State vs South Carolina predictions for college basketball Monday.
South Carolina will square off with South Carolina State in men's college basketball action at Colonial Life Arena on Monday, beginning at 4:00 PM ET.
Based on updated simulation results, Dimers' proven college basketball model predicts South Carolina as the most likely winner of the South Carolina State vs. South Carolina game.
This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.
South Carolina State vs. South Carolina prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Monday's NCAA basketball game between South Carolina State and South Carolina 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives South Carolina a 99% chance of beating South Carolina State. Our predicted final score has South Carolina winning 89-60.
According to our model, South Carolina State (+31.5) has a 54% chance of covering the spread, while the 149.5-point over/under has a 52% chance of going over.
South Carolina State vs. South Carolina odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | South Carolina State | South Carolina |
|---|---|---|
| Spread | +31.5 (-108) | -31.5 (-110) |
| Moneyline | +7000 | -100000 |
| Total | o149.5 (-105) | u149.5 (-115) |
All odds are correct at the time of publication and are subject to change.
South Carolina State vs. South Carolina picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | South Carolina State +31.5 | -108 |
| Moneyline | South Carolina State | +7000 |
| Total | Over 149.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is South Carolina State +31.5 at the spread.
South Carolina State vs. South Carolina game-day updates and essential details
Monday's men's college basketball matchup between South Carolina and South Carolina State at Colonial Life Arena is scheduled to start at 4:00 PM ET.
- Who: South Carolina State vs. South Carolina
- Date: Monday, December 22, 2025
- Time: 4:00 PM ET/1:00PM PT
- Venue: Colonial Life Arena
Conclusion
We predict South Carolina, with a 99% win probability, will likely beat South Carolina State on Monday.
AI and automation have enhanced this article to quickly deliver accurate South Carolina State vs. South Carolina insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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