South Alabama vs. Louisiana-Monroe prediction: South Alabama favored to win men's college basketball matchup [12/17/2025]

Louisiana-Monroe will square off with the favored South Alabama in men's college basketball action at Fant-Ewing Coliseum on Wednesday, beginning at 7:30 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts South Alabama as the most likely winner of the South Alabama vs. Louisiana-Monroe game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

South Alabama vs. Louisiana-Monroe prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Wednesday's NCAA basketball matchup between South Alabama and Louisiana-Monroe 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives South Alabama an 87% chance of beating Louisiana-Monroe. Our predicted final score has South Alabama winning 79-67.

According to our model, South Alabama (-11.5) has a 51% chance of covering the spread, while the over/under total of 148.5 points has a 52% chance of staying under.

South Alabama vs. Louisiana-Monroe odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Alabama vs. Louisiana-Monroe picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: