South Alabama vs. Louisiana-Monroe prediction: South Alabama favored to win men's college basketball matchup [12/17/2025]

Men's college basketball action continues on Wednesday at 7:30 PM ET as the favored South Alabama squares off with Louisiana-Monroe in men's college basketball action at Fant-Ewing Coliseum.

Based on updated simulations, Dimers' proven college basketball model projects South Alabama as the most likely winner of the South Alabama vs. Louisiana-Monroe game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

South Alabama vs. Louisiana-Monroe prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between South Alabama and Louisiana-Monroe 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives South Alabama an 84% chance of beating Louisiana-Monroe. Our predicted final score has South Alabama winning 79-68.

According to our model, South Alabama (-9.5) has a 55% chance of covering the spread, while the over/under total of 146.5 points has an equal 50-50 chance of hitting.

South Alabama vs. Louisiana-Monroe odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Alabama vs. Louisiana-Monroe picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is South Alabama -9.5 at the spread.

South Alabama vs. Louisiana-Monroe game-day updates and essential details

Wednesday's men's college basketball game between Louisiana-Monroe and South Alabama at Fant-Ewing Coliseum is scheduled to start at 7:30 PM ET.

• Who: South Alabama vs. Louisiana-Monroe
• Date: Wednesday, December 17, 2025
• Time: 7:30 PM ET/4:30PM PT
• Venue: Fant-Ewing Coliseum

Conclusion

We predict South Alabama, with an 84% win probability, will likely beat Louisiana-Monroe on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate South Alabama vs. Louisiana-Monroe insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.