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SMU vs. LSU prediction: LSU favored to win men's college basketball matchup [12/13/2025]

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Written by Dave Garofolo

Get SMU vs LSU predictions for college basketball Saturday.

SMU-LSU Predictions and Game Preview.
SMU vs. LSU men's college basketball prediction for Saturday, December 13, 2025.

LSU and SMU will meet in men's college basketball action at Smoothie King Center on Saturday, starting at 8:30PM ET.

Based on updated simulations, Dimers' advanced college basketball model gives LSU a slight edge with a 52% win probability over SMU.

This article offers an expanded analysis of Saturday's SMU vs. LSU matchup, including an expanded look at the predicted score, best bets and picks.

SMU vs. LSU prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball game between SMU and LSU 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives LSU a 52% chance of defeating SMU. Our predicted score is SMU 79-79 LSU.

According to our model, SMU (+1.5) has a 55% chance of covering the spread, while the 158.5-point over/under has an equal 50-50 chance of hitting.

While there is no way for a men's college basketball game to end in a tie, our prediction of 79-79 is based on each team's average score in the above-mentioned simulations of SMU vs. LSU.

 

SMU vs. LSU odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type SMU LSU
Spread +1.5 (-118) -1.5 (+100)
Moneyline +100 -115
Total o158.5 (-110) u158.5 (-108)

All odds are correct at the time of publication and are subject to change.

SMU vs. LSU picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread SMU +1.5 -118
Moneyline SMU +100
Total Under 158.5 -108

According to our men's college basketball best bets, the top play to make on this game is SMU +1.5 at the spread.

 

SMU vs. LSU game-day updates and essential details

Saturday's men's college basketball matchup between LSU and SMU at Smoothie King Center is scheduled to begin at 8:30PM ET.

  • Who: SMU vs. LSU
  • Date: Saturday, December 13, 2025
  • Time: 8:30PM ET/5:30PM PT
  • Venue: Smoothie King Center

Conclusion

We predict LSU, with a 52% win probability, will likely beat SMU on Saturday.

AI and automation have enhanced this article to quickly deliver accurate SMU vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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