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SIUE vs. Eastern Illinois prediction: Why SIU-Edwardsville is favored to win men's college basketball matchup [12/18/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get SIUE vs Eastern Illinois predictions for college basketball Thursday.
Eastern Illinois and SIUE are scheduled to meet in men's college basketball action at Lantz Arena on Thursday, with tipoff at 6:30 PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model projects SIU-Edwardsville as the most likely winner of the SIUE vs. Eastern Illinois game.
This article offers an expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks.
SIUE vs. Eastern Illinois prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the result of Thursday's NCAA basketball game between SIUE and Eastern Illinois 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives SIU-Edwardsville an 82% chance of defeating Eastern Illinois. Our predicted final score has SIU-Edwardsville winning 73-64.
According to our model, SIU-Edwardsville (-6.5) has a 60% chance of covering the spread, while the over/under total of 134.5 points has a 51% chance of going over.
SIUE vs. Eastern Illinois odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | SIUE | Eastern Illinois |
|---|---|---|
| Spread | -6.5 (-102) | +6.5 (-110) |
| Moneyline | -270 | +235 |
| Total | o134.5 (-112) | u134.5 (-105) |
All odds are correct at the time of publication and are subject to change.
SIUE vs. Eastern Illinois picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | SIU-Edwardsville -6.5 | -102 |
| Moneyline | SIU-Edwardsville | -270 |
| Total | Over 134.5 | -112 |
According to our men's college basketball best bets, the top play to make on this game is SIU-Edwardsville -6.5 at the spread.
SIUE vs. Eastern Illinois game-day updates and essential details
Thursday's men's college basketball game between Eastern Illinois and SIUE at Lantz Arena is scheduled to begin at 6:30 PM ET.
- Who: SIU-Edwardsville vs. Eastern Illinois
- Date: Thursday, December 18, 2025
- Time: 6:30 PM ET/3:30PM PT
- Venue: Lantz Arena
Conclusion
We predict SIU-Edwardsville, with an 82% win probability, will likely beat Eastern Illinois on Thursday.
AI and automation have enhanced this article to quickly deliver accurate SIU-Edwardsville vs. Eastern Illinois insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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