Siena vs. Iona prediction: Why Iona is favored to win men's college basketball matchup [1/2/2026]

Iona and Siena are scheduled to meet in men's college basketball action at Hynes Athletics Center on Friday, with tipoff at 7:00 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Iona as the most likely winner of the Siena vs. Iona game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Siena vs. Iona prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Friday's NCAA basketball matchup between Siena and Iona 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Iona a 56% chance of defeating Siena. Our predicted final score has Iona winning 74-72.

According to our model, the bookmakers have got it right, and Siena and Iona each have a 50% chance of covering the spread, while the over/under total of 146.5 points has a 52% chance of going over.

Siena vs. Iona odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Siena vs. Iona picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: