Seattle Mariners vs. New York Yankees Prediction, Odds, MLB Picks [5/22/2024]

Seattle Mariners vs. New York Yankees Prediction, Odds, MLB Picks [5/22/2024]

The New York Yankees and Seattle Mariners will meet in MLB action at Yankee Stadium on Wednesday, starting at 7:05PM ET.

Nestor Cortes (2-4, 3.56 ERA) will start for the Yankees, pitting him against Bryce Miller (3-4, 3.08 ERA) for the Mariners.'s comprehensive preview of Wednesday's Mariners vs. Yankees matchup includes our prediction, picks and the latest betting odds.

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Mariners vs. Yankees Prediction: Who Will Win, Cover the Run Line

We have used innovative machine learning and statistics to simulate the outcome of Wednesday's MLB game between the Mariners and Yankees 10,000 times, in line with our coverage of MLB predictions.

Our independent predictive analytics model gives the Yankees a 58% chance of beating the Mariners.

According to our model, the Mariners (+1.5) have a 60% chance of covering the run line, while the 8.5-run over/under has a 53% chance of going over.

Mariners vs. Yankees Odds [5/22/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Mariners Yankees
Run Line +1.5 (-155) -1.5 (+134)
Moneyline +136 -156
Total o8.5 (-110) u8.5 (-108)

All odds are correct at the time of publication and are subject to change.

Mariners vs. Yankees Picks

At Dimers, our predictions, coupled with the current odds, reveal the top betting picks for every game, including Mariners vs. Yankees. Our MLB best bets are based on expert modeling and analysis, as you can see.

Improve your odds with Dimers Pro. Dimers Pro subscribers get hundreds of data-driven bets daily across thousands of games. Join now to get instant access and see any potential picks for this matchup.


Mariners vs. Yankees Game Information

Wednesday's MLB action between the Yankees and Mariners at Yankee Stadium is scheduled to start at 7:05PM ET.


Our full betting coverage of the Mariners vs. Yankees includes pregame predictions, betting picks and live scores.

Calling Our Shot: Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.


We predict the Yankees, with a 58% win probability, will likely beat the Mariners on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Yankees insights, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

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Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua has a deep-rooted passion for sports and has been actively involved in sports betting for many years. Specializing in the MLB, NHL, NBA, MLS, and NFL, Jason delivers engaging game previews across these leagues. His expertise is particularly evident in his best bets for MLB, NHL, and college basketball. Additionally, Jason contributes valuable MLB and NFL props, as well as NBA first basket plays. 

Since joining Dimers in 2020 as the Head of Social and Community, Jason has also made significant contributions to the editorial department, offering daily articles that are not only well-researched but also deeply insightful. His strategic approach and collaboration with DimersBOT ensure his betting advice is top-notch.

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