Mariners vs. Diamondbacks Prediction: Arizona Predicted to Win Wednesday's MLB Matchup [6/11/2025]

The Arizona Diamondbacks will take on the Seattle Mariners in MLB action at Chase Field on Wednesday, beginning at 3:40PM ET.

The Diamondbacks will start Eduardo Rodriguez (1-3, 6.70 ERA), pitting him against Bryan Woo (5-3, 3.07 ERA) for the Mariners.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Seattle-Arizona game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Diamondbacks' chance of winning at 56%, with the Mariners at 44%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Mariners vs. Diamondbacks predictions page.

Diamondbacks vs. Mariners Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Mariners and Diamondbacks 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Diamondbacks a 56% chance of defeating the Mariners.

According to our model, the Diamondbacks (+1.5) have a 68% chance of covering the run line, while the 9-run over/under has a 52% chance of staying under.

Mariners vs. Diamondbacks Odds [6/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Mariners	Diamondbacks
Run Line	-1.5 (+155)	+1.5 (-184)
Moneyline	-102	-115
Total	o9 (-105)	u9 (-115)

All odds are correct at the time of publication and are subject to change.

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Mariners vs. Diamondbacks Picks and Best Bets

Our model's biggest edge in today's Mariners vs. Diamondbacks matchup is on the total.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Mariners vs. Diamondbacks Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Diamondbacks and Mariners at Chase Field is scheduled to commence at 3:40PM ET.

• Who: Seattle Mariners vs. Arizona Diamondbacks
• Date: Wednesday, June 11, 2025
• Time: 3:40PM ET/12:40PM PT
• Venue: Chase Field

Dimers.com's in-depth preview of Wednesday's Mariners vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

Before making any Seattle vs. Arizona picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Diamondbacks, with a 56% win probability, will likely beat the Mariners on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Mariners vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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