Jun 22, 2026
MLB picks today: Monday's MLB best bets include Red Sox vs. Rockies play [6/22/2026]
Read Article Brewers vs. Reds prediction: Why Milwaukee is favored to win Monday's MLB matchup [6/22/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Milwaukee Brewers vs Cincinnati Reds predictions for MLB Monday.
The Cincinnati Reds will square off with the Milwaukee Brewers in MLB action at Great American Ball Park on Monday, starting at 7:10 PM ET.
The Reds will send Brady Singer (3-6, 5.32 ERA) to the mound, pitting him against Brandon Woodruff (2-1, 3.60 ERA) for the Brewers.
Based on the latest simulations, Dimers' advanced MLB model predicts the Brewers as the most likely winner of the Brewers vs. Reds game.
This article offers a closer look at Monday's matchup, including best bets and picks.
Brewers vs. Reds prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Brewers and Reds, forming part of our MLB predictions coverage.
Our famous predictive model currently gives the Brewers a 55.1% chance of defeating the Reds.
According to our model, the Reds (+1.5) have a 55.7% chance of covering the run line, while the 9.5-run over/under has a 50.2% chance of staying under,.
Brewers vs. Reds odds [6/22/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Brewers | Reds |
|---|---|---|
| Run Line | -1.5 (+105) | +1.5 (-125) |
| Moneyline | -148 | +126 |
| Total | o9.5 (-104) | u9.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Brewers vs. Reds picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Reds +1.5 | -125 |
| Moneyline | Reds | +126 |
| Total | Over 9.5 | -104 |
According to our MLB best bets, the top play to make on this game is Reds +1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Brewers vs. Reds game-day updates and essential details
Monday's MLB matchup between the Reds and Brewers at Great American Ball Park is scheduled to start at 7:10 PM ET.
- Who: Milwaukee Brewers vs. Cincinnati Reds
- Date: Monday, June 22, 2026
- Time: 7:10 PM ET/4:10PM PT
- Venue: Great American Ball Park
Conclusion
We predict the Brewers, with a 55.1% win probability, will likely beat the Reds in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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