Santa Clara vs. Arizona State prediction: Why Santa Clara is favored to win men's college basketball matchup [12/13/2025]

Men's college basketball action continues on Saturday at 7:00PM ET as Santa Clara squares off with Arizona State in men's college basketball action at Lee's Family Forum.

Based on the latest simulation results, Dimers' proven college basketball model gives Santa Clara a slight edge with a 52% win probability over Arizona State.

This article offers a closer look at Saturday's Santa Clara vs. Arizona State matchup, including an expanded look at the predicted score, best bets and picks.

Santa Clara vs. Arizona State prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NCAA basketball matchup between Santa Clara and Arizona State 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Santa Clara a 52% chance of defeating Arizona State. Our predicted score is Santa Clara 77-77 Arizona State.

According to our model, Arizona State (+1.5) has a 54% chance of covering the spread, while the 154.5-point over/under has an equal 50-50 chance of hitting.

While there is no way for a men's college basketball game to end in a tie, our prediction of 77-77 is based on each team's average score in the above-mentioned simulations of Santa Clara vs. Arizona State.

Santa Clara vs. Arizona State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Santa Clara vs. Arizona State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Arizona State +1.5 at the spread.

Santa Clara vs. Arizona State game-day updates and essential details

Saturday's men's college basketball action between Arizona State and Santa Clara at Lee's Family Forum is scheduled to commence at 7:00PM ET.

• Who: Santa Clara vs. Arizona State
• Date: Saturday, December 13, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Lee's Family Forum

Conclusion

We predict Santa Clara, with a 52% win probability, will likely beat Arizona State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Santa Clara vs. Arizona State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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