San Francisco vs. Seattle prediction: Seattle favored to win men's college basketball matchup [12/28/2025]

Seattle and San Francisco will meet in men's college basketball action at Redhawk Center on Sunday, starting at 8:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects Seattle as the most likely winner of the San Francisco vs. Seattle game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

San Francisco vs. Seattle prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Sunday's NCAA basketball game between San Francisco and Seattle 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Seattle a 59% chance of beating San Francisco. Our predicted final score has Seattle winning 73-71.

According to our model, San Francisco (+2.5) has a 51% chance of covering the spread, while the over/under total of 144.5 points has an equal 50-50 chance of hitting.

San Francisco vs. Seattle odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

San Francisco vs. Seattle picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: