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San Francisco vs. Seattle prediction: Seattle favored to win men's college basketball matchup [12/28/2025]
Get San Francisco vs Seattle predictions for college basketball Sunday.

Seattle will face San Francisco in men's college basketball action at Redhawk Center on Sunday, starting at 8:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Seattle as the most likely winner of the San Francisco vs. Seattle game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
San Francisco vs. Seattle prediction: Who will win and cover?
Using innovative machine learning and statistical analysis, we have simulated the outcome of Sunday's NCAA basketball game between San Francisco and Seattle 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives Seattle a 59% chance of beating San Francisco. Our predicted final score has Seattle winning 74-71.
According to our model, San Francisco (+2.5) has a 51% chance of covering the spread, while the over/under total of 146.5 points has a 53% chance of staying under.
San Francisco vs. Seattle odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | San Francisco | Seattle |
|---|---|---|
| Spread | +2.5 (-110) | -2.5 (-105) |
| Moneyline | +125 | -144 |
| Total | o146.5 (-115) | u146.5 (-105) |
All odds are correct at the time of publication and are subject to change.
San Francisco vs. Seattle picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | San Francisco +2.5 | -110 |
| Moneyline | Seattle | -144 |
| Total | Under 146.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Under 146.5 total points.
San Francisco vs. Seattle game-day updates and essential details
Sunday's men's college basketball matchup between Seattle and San Francisco at Redhawk Center is scheduled to start at 8:00 PM ET.
- Who: San Francisco vs. Seattle
- Date: Sunday, December 28, 2025
- Time: 8:00 PM ET/5:00PM PT
- Venue: Redhawk Center
Conclusion
We predict Seattle, with a 59% win probability, will likely beat San Francisco on Sunday.
AI and automation have enhanced this article to quickly deliver accurate San Francisco vs. Seattle insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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