San Diego vs. UC San Diego prediction: UC San Diego favored to win men's college basketball matchup [12/19/2025]

UC San Diego and San Diego will lock horns in men's college basketball action at LionTree Arena on Friday, with tipoff at 10:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts UC San Diego as the most likely winner of the San Diego vs. UC San Diego game.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks.

San Diego vs. UC San Diego prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Friday's NCAA basketball matchup between San Diego and UC San Diego 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives UC San Diego an 87% chance of beating San Diego. Our predicted final score has UC San Diego winning 85-72.

According to our model, San Diego (+13.5) has a 51% chance of covering the spread, while the over/under total of 156.5 points has a 53% chance of staying under.

San Diego vs. UC San Diego odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

San Diego vs. UC San Diego picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: