San Diego Padres vs. Chicago Cubs Prediction, Odds, MLB Picks [5/8/2024]

The Chicago Cubs and San Diego Padres will meet in MLB action at Wrigley Field on Wednesday, starting at 2:20PM ET.

The Cubs will start Hayden Wesneski (2-0, 0.54 ERA), while the Padres have opted for Dylan Cease (4-2, 2.55 ERA).

Dimers.com's full preview of Wednesday's Padres vs. Cubs matchup includes our prediction, picks and the latest betting odds.

JOIN NOW: Dimers Pro unlocks +EV bets daily. We give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join Dimers Pro now for less than $1 a day!

Padres vs. Cubs Prediction: Who Will Win, Cover the Run Line

We have used advanced machine learning and data analysis to simulate the result of Wednesday's MLB matchup between the Padres and Cubs 10,000 times, in line with our coverage of MLB predictions.

Our proven predictive analytics model currently gives the Padres a 53% chance of beating the Cubs.

According to our model, the Cubs (+1.5) have a 60% chance of covering the run line, while the 7.5-run over/under has a 51% chance of going over.

Padres vs. Cubs Odds [5/8/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Padres	Cubs
Run Line	-1.5 (+135)	+1.5 (-155)
Moneyline	-134	+115
Total	o7.5 (+100)	u7.5 (-115)

All odds are correct at the time of publication and are subject to change.

Padres vs. Cubs Picks

At Dimers, our predictions, paired with the latest odds, reveal the top betting picks for every game, including Padres vs. Cubs. Our best MLB bets are based on expert modeling and analysis, as you can see.

Dimers Pro unlocks +EV bets daily. Dimers Pro subscribers get hundreds of data-driven bets daily across thousands of games. Join now to get instant access and see any potential picks for this matchup.

Padres vs. Cubs Game Information

Wednesday's MLB matchup between the Cubs and Padres at Wrigley Field is scheduled to begin at 2:20PM ET.

• Who: San Diego Padres vs. Chicago Cubs
• Date: Wednesday, May 8, 2024
• Time: 2:20PM ET / 11:20AM PT
• Venue: Wrigley Field

Our full coverage of the Padres vs. Cubs includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Conclusion

We predict the Padres, with a 53% win probability, will likely beat the Cubs on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on MLB

Stay up-to-date with the most recent MLB betting news and our analytics-driven MLB picks and parlays all season long. Plus, our World Series odds give you the latest projections and the best available odds on the World Series, American League, National League, and each division.