Royals vs. White Sox Prediction and Odds - Apr 28, 2022

The Chicago White Sox take on the Kansas City Royals in MLB action at Guaranteed Rate Field on Thursday, beginning at 2:10PM ET.

Michael Kopech (0-0, 0.64 ERA) will start for the White Sox, while the Royals will counter with Brad Keller (0-2, 2.55 ERA).

Dimers' best betting picks for Royals vs. White Sox, plus game predictions and best odds, are detailed below.

Who will win Royals vs. White Sox?

Based on trusted computer power and data, Dimers.com has simulated Thursday's Royals-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the White Sox a 63% chance of winning against the Royals.

More: Royals vs. White Sox Simulated 10,000 Times

Royals vs. White Sox Current Odds

• Run Line: White Sox -1.5 (+125), Royals +1.5 (-142)
• Moneyline: White Sox -169, Royals +150
• Total: Over/Under 7 (+100/-120)

Run Line, Moneyline and Over/Under

The White Sox are -1.5 favorites against the Royals, with +125 at DraftKings Sportsbook the best odds currently available.

For the underdog Royals (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -142.

Caesars Sportsbook currently has the best moneyline odds for the White Sox at -169, which means you can risk $169 to win $100, for a total payout of $269, if they get the W.

On the other hand, BetMGM currently has the best moneyline odds for the Royals at +150, where you can bet $100 to profit $150, earning a total payout of $250, if they win.

The Over/Under sits at 7 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, check out all the legal sportbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 56% chance of covering the run line, while the Over/Under total of 7 runs is a 52% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Royals vs. White Sox

• Run Line: White Sox -1.5 @ +125 via DraftKings Sportsbook
• Moneyline: White Sox @ -169 via Caesars Sportsbook (63% probability)
• Total: Over 7 @ +100 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on complex simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in America.

Although the Royals are more likely to cover the run line, our best bet of White Sox -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Royals vs. White Sox Betting Guide

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Kansas City vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full coverage of this Royals-White Sox matchup, including pregame predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this article for the latest betting insights before Royals vs. White Sox on Thursday April 28, 2022.

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Royals vs. White Sox 2022 Game Info

When do the White Sox play the Royals?

• Date: Thursday April 28, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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Want more MLB previews like this?

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That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to produce the most accurate MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

Finally, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.