Royals vs. Orioles Prediction and Odds - May 6, 2022

MLB action continues on Friday at 7:05PM ET as the Kansas City Royals square off with the Baltimore Orioles at Oriole Park at Camden Yards.

The Orioles will send Jordan Lyles (2-2, 4.50 ERA) to the mound, while the Royals are going with Carlos Hernández (0-1, 6.00 ERA).

Dimers' best betting picks for Royals vs. Orioles, as well as game predictions and best odds, are featured below.

This Kansas City vs. Baltimore betting preview is sponsored by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.

Who will win Royals vs. Orioles?

Based on trusted computer power and data, Dimers.com has simulated Friday's Royals-Orioles MLB game 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Orioles a 53% chance of getting the W against the Royals.

More: Royals vs. Orioles Simulated 10,000 Times

Royals vs. Orioles Game Odds

• Run Line: Orioles -1.5 (+160), Royals +1.5 (-185)
• Moneyline: Orioles -126, Royals +110
• Total: Over/Under 8 (-102/-115)

Run Line, Moneyline and Over/Under

The Orioles are listed as -1.5 favorites versus the Royals, with +160 at DraftKings Sportsbook the best odds currently available.

For the underdog Royals (+1.5) to cover the run line, PointsBet has the best odds currently on offer at -185.

FanDuel Sportsbook currently has the best moneyline odds for the Orioles at -126, which means you can risk $126 to win $100, for a total payout of $226, if they get the W.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Royals at +110, where you can bet $100 to profit $110, earning a total payout of $210, if they win.

The Over/Under is set at 8 with FanDuel Sportsbook, which currently has the best odds for the Over at -102, while Caesars Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 63% chance of covering the run line, while the 8-run Over/Under is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Royals vs. Orioles

• Run Line: Orioles -1.5 @ +160 via DraftKings Sportsbook
• Moneyline: Royals @ +110 via DraftKings Sportsbook
• Total: Over 8 @ -102 via FanDuel Sportsbook (52% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays every time.

Even though the Royals are more likely to cover the run line, our best bet of Orioles -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

And while the Orioles are more likely to win the game, according to DimersBOT, taking the Royals moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is one of the keys to being profitable in the long run.

Royals vs. Orioles Probabilities

Use our widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Kansas City vs. Baltimore, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Royals-Orioles matchup, including pregame predictions, free picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before Royals vs. Orioles on Friday May 6, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Royals vs. Orioles 2022 Game Info

When do the Orioles play the Royals?

• Date: Friday May 6, 2022
• Time: 7:05PM ET / 4:05PM PT
• Venue: Oriole Park at Camden Yards

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Want more MLB previews like this?

To get more MLB betting predictions like you've just read for Royals vs. Orioles, all you've gotta do is visit Dimers' MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can publish the best MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.