Royals vs. Mariners Prediction and Odds - Apr 22, 2022

The Seattle Mariners and Kansas City Royals are scheduled to meet in MLB at T-Mobile Park on Friday, starting at 9:40PM ET.

The Mariners will send Chris Flexen (0-2, 5.23 ERA) to the mound, pitting him against Brad Keller (0-1, 1.38 ERA) for the Royals.

Dimers' free betting picks for Royals vs. Mariners, plus game predictions and best odds, are featured below.

Who will win Royals vs. Mariners?

Based on cutting-edge machine learning and data, Dimers.com has simulated Friday's Royals-Mariners MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Mariners a 57% chance of defeating the Royals.

More: Royals vs. Mariners Simulated 10,000 Times

Royals vs. Mariners Current Odds

• Run Line: Mariners -1.5 (+170), Royals +1.5 (-182)
• Moneyline: Mariners -130, Royals +115
• Total: Over/Under 7.5 (-110/-104)

Run Line, Moneyline and Over/Under

The Mariners are -1.5 favorites against the Royals, with +170 at Caesars Sportsbook the best odds currently available.

For the underdog Royals (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -182.

Caesars Sportsbook currently has the best moneyline odds for the Mariners at -130. That means you can risk $130 to win $100, for a total payout of $230, if they get the W.

Meanwhile, PointsBet currently has the best moneyline odds for the Royals at +115, where you can bet $100 to profit $115, earning a total payout of $215, if they win.

The Over/Under for total runs scored is set at 7.5 with BetMGM, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at -104.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 63% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Royals vs. Mariners

• Run Line: Mariners -1.5 @ +170 via Caesars Sportsbook
• Moneyline: Mariners @ -130 via Caesars Sportsbook (57% probability)
• Total: Over 7.5 @ -110 via BetMGM (52% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in your state.

Although the Royals are more likely to cover the run line, our best bet of Mariners -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.

Royals vs. Mariners Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Kansas City vs. Seattle, and click or tap on See Matchup for more.

Dimers has full betting coverage of Friday's Royals-Mariners matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this page for the latest betting analysis before Royals vs. Mariners on Friday April 22, 2022.

Best Sportsbook Promo for Royals vs. Mariners

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Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Royals vs. Mariners 2022 Game Info

When do the Mariners play the Royals?

• Date: Friday April 22, 2022
• Time: 9:40PM ET / 6:40PM PT
• Venue: T-Mobile Park

Ready to join an online sportsbook and start betting on MLB? Check out the top sportsbook offers in your state.

What other MLB games are on today?

Now you've got the 411 on Royals vs. Mariners, take a look at the latest betting predictions for all upcoming MLB games in Dimers' MLB Bet Hub, where you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.