Royals vs. Cardinals Prediction and Odds - May 2, 2022

The St Louis Cardinals and Kansas City Royals lock horns in MLB at Busch Stadium on Monday, starting at 1:15PM ET.

Steven Matz (2-1, 6.11 ERA) will be on the bump for the Cardinals, pitting him against Zack Greinke (0-1, 2.86 ERA) for the Royals.

Dimers' top betting picks for Royals vs. Cardinals, plus game predictions and best odds, are featured in this article.

Today's Kansas City vs. St Louis betting analysis is proudly sponsored by PointsBet, which has an awesome 5x $100 Risk-Free Bets promo for new customers.

Who will win Royals vs. Cardinals?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Monday's Royals-Cardinals MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Cardinals a 62% chance of winning against the Royals.

More: Free Betting Analysis for Royals vs. Cardinals

Royals vs. Cardinals Game Odds

• Run Line: Cardinals -1.5 (+135), Royals +1.5 (-145)
• Moneyline: Cardinals -155, Royals +145
• Total: Over/Under 7 (-120/+105)

Run Line, Moneyline and Over/Under

The Cardinals are -1.5 favorites versus the Royals, with +135 at BetMGM the best odds currently available.

For the underdog Royals (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -145.

BetMGM currently has the best moneyline odds for the Cardinals at -155, which means you can risk $155 to win $100, for a total payout of $255, if they get the W.

On the other hand, PointsBet currently has the best moneyline odds for the Royals at +145, where you can bet $100 to profit $145, earning a total payout of $245, if they win.

The Over/Under is set at 7 with BetMGM, which currently has the best odds for the Over at -120, while DraftKings Sportsbook currently has the best odds for the Under at +105.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Royals (+1.5) are a 57% chance of covering the run line, while the Over/Under total of 7 runs is a 55% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Royals vs. Cardinals

• Run Line: Cardinals -1.5 @ +135 via BetMGM (0.4% edge)
• Moneyline: Cardinals @ -155 via BetMGM (62% probability)
• Total: Over 7 @ -120 via BetMGM (55% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in America.

Although the Royals are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Royals vs. Cardinals Probabilities

Use our dynamic widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Kansas City vs. St Louis, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Monday's Royals-Cardinals matchup, including pregame predictions, computer picks, and live scores.

Remember, DimersBOT updates frequently, so check this article for any changes to our betting analysis ahead of Royals vs. Cardinals on Monday May 2, 2022.

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Royals vs. Cardinals 2022 Game Info

When do the Cardinals play the Royals?

• Date: Monday May 2, 2022
• Time: 1:15PM ET / 10:15AM PT
• Venue: Busch Stadium

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What other MLB games are on today?

Now you've got the 411 on Royals vs. Cardinals, get the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, and our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.