Reds vs. Padres Prediction and Odds - Apr 20, 2022

The San Diego Padres take on the Cincinnati Reds in MLB action at PETCO Park on Wednesday, starting at 4:10PM EDT.

The Padres will send MacKenzie Gore (0-0, 3.38 ERA) to the mound, while the Reds are going with Vladimir Gutierrez (0-2, 5.40 ERA).

Dimers' best betting picks for Reds vs. Padres, plus game predictions and best odds, are detailed in this article.

Who will win Reds vs. Padres?

Based on advanced machine learning and data, Dimers.com has simulated Wednesday's Reds-Padres MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Padres a 67% chance of beating the Reds.

More: Reds vs. Padres Simulated 10K Times

Reds vs. Padres Current Odds

• Run Line: Padres -1.5 (+105), Reds +1.5 (-120)
• Moneyline: Padres -195, Reds +175
• Total: Over/Under 8.5 (+100/-114)

Run Line, Moneyline and Over/Under

The Padres are -1.5 favorites versus the Reds, with +105 at DraftKings Sportsbook the best odds currently available.

For the underdog Reds (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -120.

DraftKings Sportsbook currently has the best moneyline odds for the Padres at -195. That means you can risk $195 to win $100, for a total payout of $295, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Reds at +175, where you can bet $100 to profit $175, earning a total payout of $275, if they win.

The Over/Under for total runs scored sits at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -114.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 51% chance of covering the run line, while the Over/Under total of 8.5 runs is a 53% chance of going Under.

More: Predictions for Every MLB Game

Best Bets for Reds vs. Padres

• Run Line: Padres -1.5 @ +105 via DraftKings Sportsbook
• Moneyline: Padres @ -195 via DraftKings Sportsbook (67% probability)
• Total: Under 8.5 @ -114 via FanDuel Sportsbook (53% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to bring you the best possible plays every day of the year.

Even though the Reds are more likely to cover the run line, our best bet of Padres -1.5 is based on the likelihood of that happening, according to DimersBOT, and the best odds available.

Reds vs. Padres Betting Guide

Use our interactive widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for Cincinnati vs. San Diego, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Reds-Padres matchup, including pre-game predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates frequently, so refresh this article for any changes to our betting insights before Reds vs. Padres on Wednesday April 20, 2022.

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Reds vs. Padres 2022 Game Info

When do the Padres play the Reds?

• Date: Wednesday April 20, 2022
• Time: 4:10PM EDT / 1:10PM PDT
• Venue: PETCO Park

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What MLB games are on today?

The Reds and Padres aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single MLB matchup in our MLB Bet Hub page.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.