Reds vs. Padres Prediction and Odds - Apr 18, 2022

MLB action continues on Monday at 9:40PM EDT as the Cincinnati Reds square off with the San Diego Padres at PETCO Park.

Sean Manaea (1-1, 1.38 ERA) will get the ball for the Padres, up against Nick Lodolo (0-1, 11.25 ERA) for the Reds.

Dimers' top betting picks for Reds vs. Padres, as well as game predictions and best odds, are detailed below.

Who will win Reds vs. Padres?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Monday's Reds-Padres MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Padres a 63% chance of winning against the Reds.

More: Reds vs. Padres Simulated 10K Times

Reds vs. Padres Current Odds

• Run Line: Padres -1.5, Reds +1.5
• Moneyline: Padres -175, Reds +165
• Total: Over/Under 7.5

Run Line, Moneyline and Over/Under

The Padres are -1.5 favorites against the Reds, with +120 at BetMGM the best odds currently available.

For the underdog Reds (+1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -128.

BetMGM currently has the best moneyline odds for the Padres at -175, which means you can risk $175 to win $100, for a total payout of $275, if they get the W.

Meanwhile, PointsBet currently has the best moneyline odds for the Reds at +165, where you can bet $100 to profit $165, earning a total payout of $265, if they win.

The Over/Under sits at 7.5 with PointsBet, which currently has the best odds for the Over at +105, while Caesars Sportsbook currently has the best odds for the Under at -120.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 57% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Under.

More: Live Win Probabilities for All Major Sports

Best Bets for Reds vs. Padres

• Run Line: Reds +1.5 @ -128 via FanDuel Sportsbook (57% probability)
• Moneyline: Reds @ +165 via PointsBet
• Total: Over 7.5 @ +105 via PointsBet

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in your state.

While the Padres are more likely to win the game, according to DimersBOT, betting on the Reds moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published here at Dimers.com is crucial to achieving long-term profitability.

Furthermore, despite the Under being more likely to hit on this occasion, Over 7.5 is our best bet on account of the better odds (+105) that are available from PointsBet.

Reds vs. Padres Probabilities

Use our widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cincinnati vs. San Diego, and click or tap on See Matchup for more.

Dimers has full coverage of Monday's Reds-Padres matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so check this page for the latest betting analysis before Reds vs. Padres on Monday April 18, 2022.

Get a Risk-Free Bet for Reds vs. Padres

Do you want to bet on Cincinnati vs. San Diego? Join Betway now and get a bet risk free up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA, which you can use on Monday's Reds-Padres game.

Simply click or tap on this exclusive Betway link and create an account – it's easy and takes no time at all.

Then, deposit funds and place a bet up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA on Reds vs. Padres. If you don't win your bet, Betway will refund it in site credit!

This offer is available to all new Betway users. How good is that!

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Reds vs. Padres 2022 Game Info

When do the Padres play the Reds?

• Date: Monday April 18, 2022
• Time: 9:40PM EDT / 6:40PM PDT
• Venue: PETCO Park

Want to join an online sportsbook and start betting on MLB now? We've listed the best available sign-up offers for each and every legal betting state.

What MLB games are on today?

Now you've got the 411 on Reds vs. Padres, get the latest betting coverage for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.