MLB- More Betting
Reds vs. Cardinals Prediction and Odds - Jul 16, 2022

The St. Louis Cardinals face the Cincinnati Reds in MLB action at Busch Stadium on Saturday, starting at 2:15PM ET.
Miles Mikolas (6-7, 2.62 ERA) will start on the mound for the Cardinals, while the Reds will counter with Nick Lodolo (2-2, 4.44 ERA).
Dimers' best betting picks for Reds vs. Cardinals, plus game predictions and betting odds, are detailed below.
Who will win Reds vs. Cardinals?
Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's Reds-Cardinals MLB matchup 10,000 times.
Dimers' independent predictive analytics model, DimersBOT, gives the Cardinals a 60% chance of beating the Reds.
More: Full Betting Guide for Reds vs. Cardinals
Reds vs. Cardinals Odds
- Run Line: Cardinals -1.5 (+120), Reds +1.5 (-135)
- Moneyline: Cardinals -161, Reds +146
- Total: Over/Under 8.5 (+100/-115)
Run Line, Moneyline and Over/Under
The Cardinals are currently -1.5 favorites versus the Reds, with +120 at DraftKings Sportsbook the best odds currently available.
For the underdog Reds (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -135.
Caesars Sportsbook currently has the best moneyline odds for the Cardinals at -161. That means you can risk $161 to win $100, for a total payout of $261, if they get the W.
Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Reds at +146, where you can bet $100 to profit $146, earning a total payout of $246, if they win.
The Over/Under for total runs scored is set at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while PointsBet currently has the best odds for the Under at -115.
As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.
According to DimersBOT, the Reds (+1.5) are a 58% chance of covering the run line, while the 8.5-run Over/Under is a 51% chance of going Under.
More: Best Bets Today for All Major Sports
Best Bets for Reds vs. Cardinals
- Run Line: Reds +1.5 @ -135 via BetMGM (58% probability)
- Moneyline: Reds @ +146 via FanDuel Sportsbook
- Total: Over 8.5 @ +100 via Caesars Sportsbook
Dimers' best bets are based on world-class modeling and gambling expertise to bring you the best possible plays every day of the year.
While the Cardinals are more likely to win the game, according to DimersBOT, taking the Reds moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently available.
Taking advantage of the edges published here at Dimers.com is pivotal to achieving long-term profitability as a bettor.
Furthermore, despite the Under being more likely to hit on this occasion, Over 8.5 is our best bet owing to the better odds (+100) that are available from Caesars Sportsbook.
Reds vs. Cardinals Probabilities
Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Cincinnati vs. St. Louis, and click or tap on See Matchup to reveal more.
Dimers has full coverage of Saturday's Reds-Cardinals matchup, including pregame predictions, computer picks, and live win probabilities.
Remember, DimersBOT updates regularly, so keep an eye on this article for the latest betting insights before Reds vs. Cardinals on Saturday July 16, 2022.
Best Sportsbook Promo for Reds vs. Cardinals
Do you want to bet on Cincinnati vs. St. Louis? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Saturday's Reds-Cardinals game.
All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.
Then, make your first deposit and place a bet up to $1,000 on Reds vs. Cardinals. If you don't win your bet, FanDuel Sportsbook will refund it in site credit!
This offer is available to all new FanDuel Sportsbook users – no promo code needed!
Note: When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial relationship with (such as a sportsbook), we may receive a referral fee. Thank you for supporting the sponsors who make Dimers possible.
Reds vs. Cardinals 2022 Game Info
Saturday's action between the Cardinals and Reds at Busch Stadium is scheduled to commence at 2:15PM ET.
- Who: St. Louis Cardinals vs. Cincinnati Reds
- Date: Saturday July 16, 2022
- Time: 2:15PM ET / 11:15AM PT
- Venue: Busch Stadium
Enjoy Dimers and want to keep the site free? Every time you sign up and bet with a sportsbook featured here, we get paid a small fee.
These fees help us keep Dimers free for everyone. So, if you like what you see, support us by joining one of our trusted sports betting partners today.
Want more MLB analysis like this?
To get more MLB betting predictions like you've just read for Reds vs. Cardinals, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!
We use the power of predictive analytics to find value in the markets so we can write the best MLB betting previews available. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.
So, get ahead of the game and beat the bookies today – it's only a click away.
Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.
