Red Sox vs. Blue Jays Prediction and Odds - Apr 28, 2022

MLB action continues on Thursday at 3:07PM ET as the Boston Red Sox take on the Toronto Blue Jays at Rogers Centre.

Alek Manoah (3-0, 2.00 ERA) will start on the mound for the Blue Jays, up against Garrett Whitlock (1-0, 0.66 ERA) for the Red Sox.

Dimers' top betting picks for Red Sox vs. Blue Jays, plus game predictions and best odds, are detailed in this article.

Who will win Red Sox vs. Blue Jays?

Based on trusted computer power and data, Dimers.com has simulated Thursday's Red Sox-Blue Jays MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Blue Jays a 56% chance of beating the Red Sox.

More: Red Sox vs. Blue Jays Simulated 10,000 Times

Red Sox vs. Blue Jays Odds

• Run Line: Blue Jays -1.5 (+155), Red Sox +1.5 (-175)
• Moneyline: Blue Jays -140, Red Sox +125
• Total: Over/Under 7 (-110/+105)

Run Line, Moneyline and Over/Under

The Blue Jays are currently -1.5 favorites against the Red Sox, with +155 at DraftKings Sportsbook the best odds currently available.

For the underdog Red Sox (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -175.

PointsBet currently has the best moneyline odds for the Blue Jays at -140, which means you can risk $140 to win $100, for a total payout of $240, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Red Sox at +125, where you can bet $100 to profit $125, earning a total payout of $225, if they win.

The Over/Under for total runs scored sits at 7 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at +105.

As always, check out all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Red Sox (+1.5) are a 63% chance of covering the run line, while the 7-run Over/Under is a 55% chance of going Over.

More: Predictions for Every MLB Matchup

Best Bets for Red Sox vs. Blue Jays

• Run Line: Red Sox +1.5 @ -175 via BetMGM (63% probability)
• Moneyline: Red Sox @ +125 via Caesars Sportsbook
• Total: Over 7 @ -110 via Caesars Sportsbook (55% probability)

Dimers' best bets are based on world-class simulations and betting intelligence to bring you the best possible plays 24/7.

While the Blue Jays are more likely to win the game, according to DimersBOT, taking the Red Sox moneyline is the best option due to the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is crucial to being profitable in the long run.

Red Sox vs. Blue Jays Betting Guide

Use our widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Boston vs. Toronto, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Thursday's Red Sox-Blue Jays matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep checking this article for any changes to our betting analysis ahead of Red Sox vs. Blue Jays on Thursday April 28, 2022.

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Red Sox vs. Blue Jays 2022 Game Info

When do the Blue Jays play the Red Sox?

• Date: Thursday April 28, 2022
• Time: 3:07PM ET / 12:07PM PT
• Venue: Rogers Centre

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What MLB games are on today?

The Red Sox and Blue Jays aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for each and every MLB matchup via our MLB Predictions page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out today!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.