Red Sox vs. Blue Jays Prediction and Odds - Apr 27, 2022

The Toronto Blue Jays take on the Boston Red Sox in MLB action at Rogers Centre on Wednesday, commencing at 7:07PM ET.

Ross Stripling (0-0, 4.50 ERA) will be on the bump for the Blue Jays, pitting him against Michael Wacha (1-0, 1.88 ERA) for the Red Sox.

Dimers' best betting picks for Red Sox vs. Blue Jays, plus game predictions and best odds, are detailed below.

Who will win Red Sox vs. Blue Jays?

Using cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Red Sox-Blue Jays MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Blue Jays a 53% chance of winning against the Red Sox.

More: Full Betting Guide for Red Sox vs. Blue Jays

Red Sox vs. Blue Jays Odds

• Run Line: Blue Jays -1.5 (+160), Red Sox +1.5 (-161)
• Moneyline: Blue Jays -120, Red Sox +120
• Total: Over/Under 9 (+105/-120)

Run Line, Moneyline and Over/Under

The Blue Jays are -1.5 favorites versus the Red Sox, with +160 at PointsBet the best odds currently available.

For the underdog Red Sox (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -161.

BetMGM currently has the best moneyline odds for the Blue Jays at -120. That means you can risk $120 to win $100, for a total payout of $220, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Red Sox at +120, where you can put down $100 to profit $120, earning a total payout of $220, if they win.

The Over/Under sits at 9 with DraftKings Sportsbook, which currently has the best odds for the Over at +105, while Caesars Sportsbook currently has the best odds for the Under at -120.

As always, make sure you check all the online sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Red Sox (+1.5) are a 64% chance of covering the run line, while the 9-run Over/Under is a 52% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Red Sox vs. Blue Jays

• Run Line: Red Sox +1.5 @ -161 via Caesars Sportsbook (64% probability)
• Moneyline: Red Sox @ +120 via Caesars Sportsbook (1.7% edge)
• Total: Over 9 @ +105 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make smarter investments with the legal sportsbooks in the USA.

While the Blue Jays are more likely to win the game, according to DimersBOT, taking the Red Sox moneyline is the best option because of the 1.7% edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers is crucial to being a profitable sports bettor in the long run.

Red Sox vs. Blue Jays Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Boston vs. Toronto, and click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Red Sox-Blue Jays matchup, including pregame predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so check this article for the latest betting analysis before Red Sox vs. Blue Jays on Wednesday April 27, 2022.

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Red Sox vs. Blue Jays 2022 Game Info

When do the Blue Jays play the Red Sox?

• Date: Wednesday April 27, 2022
• Time: 7:07PM ET / 4:07PM PT
• Venue: Rogers Centre

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What MLB games are on today?

Now you've got the 411 on Red Sox vs. Blue Jays, see the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, and our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds available.