Rays vs. White Sox Prediction and Odds - Apr 16, 2022

The Chicago White Sox square off with the Tampa Bay Rays in MLB action at Guaranteed Rate Field on Saturday, beginning at 2:10PM EDT.

The White Sox will send Michael Kopech (0-0, 2.25 ERA) to the mound, while the Rays will counter with Corey Kluber (0-0, 0.00 ERA).

Dimers' top betting picks for Rays vs. White Sox, as well as game predictions and best odds, are featured below.

Who will win Rays vs. White Sox?

Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's Rays-White Sox MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the White Sox a 55% chance of getting the W against the Rays.

More: Free Betting Guide for Rays vs. White Sox

Rays vs. White Sox Game Odds

• Run Line: White Sox -1.5, Rays +1.5
• Moneyline: White Sox -130, Rays +115
• Total: Over/Under 8

Run Line, Moneyline and Over/Under

The White Sox are -1.5 favorites against the Rays, with +155 at DraftKings Sportsbook the best odds currently available.

For the underdog Rays (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at -169.

Caesars Sportsbook currently has the best moneyline odds for the White Sox at -130, which means you can risk $130 to win $100, for a total payout of $230, if they get the W.

Meanwhile, BetMGM currently has the best moneyline odds for the Rays at +115, where you can bet $100 to profit $115, earning a total payout of $215, if they win.

The Over/Under for total runs scored is set at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -105.

As always, make sure you check all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Rays (+1.5) are a 60% chance of covering the run line, while the 8-run Over/Under is a 56% chance of going Over.

More: Live Scores for All Major Sports

Best Bets for Rays vs. White Sox

• Run Line: White Sox -1.5 @ +155 via DraftKings Sportsbook (0.3% edge)
• Moneyline: Rays @ +115 via BetMGM
• Total: Over 8 @ -105 via Caesars Sportsbook (56% probability) 🔥

When you see a 🔥, you know you've found one of Dimers' best bets of the day across all sports.

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in your state.

Even though the Rays are more likely to cover the run line, our best bet of White Sox -1.5 is based on the likelihood of that happening, according to DimersBOT, and the top odds available.

And while the White Sox are more likely to win the game, according to DimersBOT, betting on the Rays moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers.com is pivotal to being profitable in the long run.

Rays vs. White Sox Probabilities

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Tampa Bay vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full coverage of Saturday's Rays-White Sox matchup, including pre-game predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for the latest betting analysis before Rays vs. White Sox on Saturday April 16, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Rays vs. White Sox 2022 Game Info

When do the White Sox play the Rays?

• Date: Saturday April 16, 2022
• Time: 2:10PM EDT / 11:10AM PDT
• Venue: Guaranteed Rate Field

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Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Rays vs. White Sox, all you've gotta do is visit Dimers' MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the best MLB betting previews available. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.