MLB- More Betting
Rays vs. Mariners Prediction and Odds - May 6, 2022

The Seattle Mariners and Tampa Bay Rays meet in MLB at T-Mobile Park on Friday, starting at 9:40PM ET.
Logan Gilbert (4-0, 0.64 ERA) will get the ball for the Mariners, up against Matt Wisler (1-0, 1.50 ERA) for the Rays.
Dimers' free betting picks for Rays vs. Mariners, plus game predictions and best odds, are detailed below.
This Tampa Bay vs. Seattle betting analysis is presented by PointsBet, which has a 5x $100 Risk-Free Bets promo for new customers.
Who will win Rays vs. Mariners?
Based on trusted computer power and data, Dimers.com has simulated Friday's Rays-Mariners MLB game 10,000 times.
Dimers' leading predictive analytics model, DimersBOT, gives the Mariners a 56% chance of winning against the Rays.
More: Full Betting Analysis for Rays vs. Mariners
Rays vs. Mariners Game Odds
- Run Line: Mariners -1.5 (+170), Rays +1.5 (-195)
- Moneyline: Mariners -125, Rays +110
- Total: Over/Under 7 (-105/-110)
Run Line, Moneyline and Over/Under
The Mariners are -1.5 favorites against the Rays, with +170 at BetMGM the best odds currently available.
For the underdog Rays (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at -195.
BetMGM currently has the best moneyline odds for the Mariners at -125. That means you can risk $125 to win $100, for a total payout of $225, if they get the W.
Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Rays at +110, where you can bet $100 to profit $110, earning a total payout of $210, if they win.
The Over/Under is set at 7 with PointsBet, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at -110.
As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.
According to DimersBOT, the Rays (+1.5) are a 63% chance of covering the run line, while the 7-run Over/Under is a 54% chance of going Over.
More: Live Scores for All Major Sports
Best Bets for Rays vs. Mariners
- Run Line: Mariners -1.5 @ +170 via BetMGM (0.2% edge)
- Moneyline: Mariners @ -125 via BetMGM (56% probability)
- Total: Over 7 @ -105 via PointsBet (54% probability)
Dimers' best bets are based on world-class simulations and betting intelligence to bring you the best possible plays 24/7/365.
Even though the Rays are more likely to cover the run line, our best bet of Mariners -1.5 is based on the expectation of that happening, according to DimersBOT, and the top odds available.
Rays vs. Mariners Probabilities
Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Tampa Bay vs. Seattle, and click or tap on See Matchup to reveal more.
Dimers has full coverage of Friday's Rays-Mariners matchup, including pregame predictions, top betting picks, and live updates.
Don't forget, DimersBOT updates often, so check this page for any changes to our betting insights ahead of Rays vs. Mariners on Friday May 6, 2022.
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Rays vs. Mariners 2022 Game Info
When do the Mariners play the Rays?
- Date: Friday May 6, 2022
- Time: 9:40PM ET / 6:40PM PT
- Venue: T-Mobile Park
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