Rangers vs. Astros Prediction and Odds - May 21, 2022

The Houston Astros face the Texas Rangers in MLB action at Minute Maid Park on Saturday, starting at 7:10PM ET.

The Astros will send Justin Verlander (5-1, 1.38 ERA) to the mound, pitting him against Jon Gray (1-1, 5.73 ERA) for the Rangers.

Dimers' best betting picks for Rangers vs. Astros, as well as game predictions and best odds, are featured in this article.

This Texas vs. Houston betting analysis is brought to you by PointsBet, which has a 5x $100 Risk-Free Bets promo for new users.

Who will win Rangers vs. Astros?

Based on trusted machine learning and data, Dimers.com has simulated Saturday's Rangers-Astros MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Astros a 66% chance of winning against the Rangers .

More: Free Betting Guide for Rangers vs. Astros

Rangers vs. Astros Current Odds

• Run Line: Astros -1.5 (+102), Rangers +1.5 (+100)
• Moneyline: Astros -210, Rangers +220
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Astros are -1.5 favorites against the Rangers, with +102 at FanDuel Sportsbook the best odds currently available.

For the underdog Rangers (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at +100.

FanDuel Sportsbook currently has the best moneyline odds for the Astros at -210. That means you can risk $210 to win $100, for a total payout of $310, if they get the W.

On the other hand, Caesars Sportsbook currently has the best moneyline odds for the Rangers at +220, where you can put down $100 to profit $220, earning a total payout of $320, if they win.

The Over/Under sits at 7.5 with PointsBet, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at -105.

As always, make sure you check all the legal sportbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Rangers (+1.5) are a 54% chance of covering the run line, while the Over/Under total of 7.5 runs is a 52% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Rangers vs. Astros

• Run Line: Rangers +1.5 @ +100 via Caesars Sportsbook (54% probability) 🔥
• Moneyline: Rangers @ +220 via Caesars Sportsbook (3.1% edge)
• Total: Over 7.5 @ -110 via PointsBet (52% probability)

Any time you see a 🔥, you know it's one of our best bets of the day across all major pro and college sports.

Dimers' best bets are based on detailed simulations and betting intelligence to help you make smarter decisions with the legal sportsbooks in your state.

While the Astros are more likely to win the game, according to DimersBOT, betting on the Rangers moneyline is the best option due to the 3.1% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers is pivotal to achieving long-term profitability as a bettor.

Rangers vs. Astros Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Texas vs. Houston, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Rangers-Astros matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this page for any changes to our betting analysis before Rangers vs. Astros on Saturday May 21, 2022.

Best Sportsbook Promo for Rangers vs. Astros

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Rangers vs. Astros 2022 Game Info

Saturday's game between the Astros and Rangers at Minute Maid Park is scheduled to begin at 7:10PM ET.

• Date: Saturday May 21, 2022
• Time: 7:10PM ET / 4:10PM PT
• Venue: Minute Maid Park

Want to join an online sportsbook and start betting on MLB now? We've got access to the best available sign-up offers in each legal betting state.

What other MLB games are on today?

The Rangers and Astros aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single MLB matchup via our MLB Predictions section.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.