Quinnipiac vs. Iona prediction: Why Iona is favored to win men's college basketball matchup [12/5/2025]

Iona will square off with Quinnipiac in men's college basketball action at Hynes Athletics Center on Friday, beginning at 7:00PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Iona as the most likely winner of the Quinnipiac vs. Iona game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Quinnipiac vs. Iona prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Friday's NCAA basketball matchup between Quinnipiac and Iona 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Iona a 58% chance of defeating Quinnipiac. Our predicted final score has Iona winning 81-78.

According to our model, Quinnipiac (+3.5) has a 58% chance of covering the spread, while the over/under total of 161.5 points has a 52% chance of staying under.

Quinnipiac vs. Iona odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Quinnipiac vs. Iona picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: