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Quinnipiac vs. Hofstra prediction: Hofstra favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Quinnipiac vs Hofstra predictions for college basketball Sunday.

Quinnipiac-Hofstra Predictions and Game Preview.
Quinnipiac vs. Hofstra men's college basketball prediction for Sunday, December 21, 2025.

Hofstra and Quinnipiac will lock horns in men's college basketball action at David S. Mack Sports and Exhibition Complex on Sunday, with tipoff at 1:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Hofstra as the most likely winner of the Quinnipiac vs. Hofstra game.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Quinnipiac vs. Hofstra prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Sunday's NCAA basketball game between Quinnipiac and Hofstra 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Hofstra a 78% chance of defeating Quinnipiac. Our predicted final score has Hofstra winning 77-69.

According to our model, Hofstra (-6.5) has a 57% chance of covering the spread, while the over/under total of 147.5 points has a 52% chance of going over.

 

Quinnipiac vs. Hofstra odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type Quinnipiac Hofstra
Spread +6.5 (-102) -6.5 (-115)
Moneyline +245 -300
Total o147.5 (-106) u147.5 (-110)

All odds are correct at the time of publication and are subject to change.

Quinnipiac vs. Hofstra picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Hofstra -6.5 -115
Moneyline Hofstra -300
Total Over 147.5 -106

According to our men's college basketball best bets, the top play to make on this game is Hofstra -6.5 at the spread.

 

Quinnipiac vs. Hofstra game-day updates and essential details

Sunday's men's college basketball action between Hofstra and Quinnipiac at David S. Mack Sports and Exhibition Complex is scheduled to commence at 1:00 PM ET.

  • Who: Quinnipiac vs. Hofstra
  • Date: Sunday, December 21, 2025
  • Time: 1:00 PM ET/10:00AM PT
  • Venue: David S. Mack Sports and Exhibition Complex

Conclusion

We predict Hofstra, with a 78% win probability, will likely beat Quinnipiac on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Quinnipiac vs. Hofstra insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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