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Quinnipiac vs. Hofstra prediction: Hofstra favored to win men's college basketball matchup [12/21/2025]
Get Quinnipiac vs Hofstra predictions for college basketball Sunday.

Men's college basketball action continues on Sunday at 1:00 PM ET as Quinnipiac faces off with the favored Hofstra in men's college basketball action at David S. Mack Sports and Exhibition Complex.
Based on updated simulation results, Dimers' proven college basketball model projects Hofstra as the most likely winner of the Quinnipiac vs. Hofstra game.
This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Quinnipiac vs. Hofstra prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Sunday's NCAA basketball matchup between Quinnipiac and Hofstra 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model currently gives Hofstra a 78% chance of defeating Quinnipiac. Our predicted final score has Hofstra winning 77-69.
According to our model, Hofstra (-6.5) has a 57% chance of covering the spread, while the over/under total of 146.5 points has an equal 50-50 chance of hitting.
Quinnipiac vs. Hofstra odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Quinnipiac | Hofstra |
|---|---|---|
| Spread | +6.5 (-110) | -6.5 (-110) |
| Moneyline | +235 | -275 |
| Total | o146.5 (-105) | u146.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Quinnipiac vs. Hofstra picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Hofstra -6.5 | -110 |
| Moneyline | Hofstra | -275 |
| Total | Over 146.5 | -105 |
According to our best men's college basketball bets, the top play to make on this game is Hofstra -6.5 at the spread.
Quinnipiac vs. Hofstra game-day updates and essential details
Sunday's men's college basketball matchup between Hofstra and Quinnipiac at David S. Mack Sports and Exhibition Complex is scheduled to commence at 1:00 PM ET.
- Who: Quinnipiac vs. Hofstra
- Date: Sunday, December 21, 2025
- Time: 1:00 PM ET/10:00AM PT
- Venue: David S. Mack Sports and Exhibition Complex
Conclusion
We predict Hofstra, with a 78% win probability, will likely beat Quinnipiac on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Quinnipiac vs. Hofstra insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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