Princeton vs. Loyola Chicago prediction: Loyola Chicago favored to win men's college basketball matchup [12/6/2025]

Loyola Chicago will square off with Princeton in men's college basketball action at Joseph J. Gentile Arena on Saturday, commencing at 2:30PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Loyola Chicago as the most likely winner of the Princeton vs. Loyola Chicago game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Princeton vs. Loyola Chicago prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Princeton and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Loyola Chicago a 71% chance of beating Princeton. Our predicted final score has Loyola Chicago winning 72-66.

According to our model, the bookmakers have got it right, and Princeton and Loyola Chicago each have a 50% chance of covering the spread, while the 135.5-point over/under has a 53% chance of going over.

Princeton vs. Loyola Chicago odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Princeton vs. Loyola Chicago picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: