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Princeton vs. Loyola Chicago prediction: Loyola Chicago favored to win men's college basketball matchup [12/6/2025]

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Written by Dave Garofolo

Get Princeton vs Loyola Chicago predictions for college basketball Saturday.

Princeton-Loyola Chicago Predictions and Game Preview.
Princeton vs. Loyola Chicago men's college basketball prediction for Saturday, December 6, 2025.

Loyola Chicago will square off with Princeton in men's college basketball action at Joseph J. Gentile Arena on Saturday, starting at 2:30PM ET.

Based on updated simulations, Dimers' proven college basketball model projects Loyola Chicago as the most likely winner of the Princeton vs. Loyola Chicago game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Princeton vs. Loyola Chicago prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Saturday's NCAA basketball game between Princeton and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Loyola Chicago a 74% chance of defeating Princeton. Our predicted final score has Loyola Chicago winning 72-65.

According to our model, Loyola Chicago (-6.5) has a 51% chance of covering the spread, while the 136.5-point over/under has a 53% chance of going over.

 

Princeton vs. Loyola Chicago odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Princeton Loyola Chicago
Spread +6.5 (-118) -6.5 (-102)
Moneyline +230 -258
Total o136.5 (-110) u136.5 (-105)

All odds are correct at the time of publication and are subject to change.

Princeton vs. Loyola Chicago picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Loyola Chicago -6.5 -102
Moneyline Loyola Chicago -258
Total Over 136.5 -110

According to our men's college basketball best bets, the top play to make on this game is Loyola Chicago to win.

 

Princeton vs. Loyola Chicago game-day updates and essential details

Saturday's men's college basketball matchup between Loyola Chicago and Princeton at Joseph J. Gentile Arena is scheduled to start at 2:30PM ET.

  • Who: Princeton vs. Loyola Chicago
  • Date: Saturday, December 6, 2025
  • Time: 2:30PM ET/11:30AM PT
  • Venue: Joseph J. Gentile Arena

 

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Conclusion

We predict Loyola Chicago, with a 74% win probability, will likely beat Princeton on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Princeton vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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