Prairie View A&M vs. South Dakota prediction: South Dakota favored to win men's college basketball matchup [12/13/2025]

South Dakota will square off with Prairie View A&M in men's college basketball action at Sanford Coyote Sports Center on Saturday, starting at 2:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts South Dakota as the most likely winner of the Prairie View A&M vs. South Dakota game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Prairie View A&M vs. South Dakota prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Prairie View A&M and South Dakota 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives South Dakota a 77% chance of defeating Prairie View A&M. Our predicted final score has South Dakota winning 85-77.

According to our model, the bookmakers have got it right, and Prairie View A&M and South Dakota each have a 50% chance of covering the spread, while the 166.5-point over/under has a 54% chance of staying under.

Prairie View A&M vs. South Dakota odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Prairie View A&M vs. South Dakota picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: