Prairie View A&M vs. LSU prediction: LSU favored to win men's college basketball matchup [12/22/2025]

Men's college basketball action continues on Monday at 7:00 PM ET as Prairie View A&M locks horns with LSU in men's college basketball action at Pete Maravich Assembly Center.

Based on the latest simulations, Dimers' proven college basketball model projects LSU as the most likely winner of the Prairie View A&M vs. LSU game.

This article offers a closer look at Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Prairie View A&M vs. LSU prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Monday's NCAA basketball game between Prairie View A&M and LSU 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives LSU a 98% chance of defeating Prairie View A&M. Our predicted final score has LSU winning 94-66.

According to our model, Prairie View A&M (+31.5) has a 55% chance of covering the spread, while the over/under total of 161.5 points has an equal 50-50 chance of hitting.

Prairie View A&M vs. LSU odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Prairie View A&M vs. LSU picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: